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石斛碱 /Dendrobine {[allProObj[0].p_purity_real_show]}

货号:A664519 同义名: (–)-Dendrobine

Dendrobine 是从金钗石斛中分离出的生物碱。Dendrobine 对甲型流感病毒 (H1N1) A/FM-1/1/47 的 IC50 为 3.39 μM,对 A/Puerto Rico/8/34 H274Y (H1N1) 的 IC50 为 2.16 μM,对 A/Aichi/2/68 (H3N2) 的 IC50 为 5.32 μM,显示出抗病毒活性。

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There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.

Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Dendrobine 化学结构 CAS号:2115-91-5
Dendrobine 化学结构
CAS号:2115-91-5
Dendrobine 3D分子结构
CAS号:2115-91-5
Dendrobine 化学结构 CAS号:2115-91-5
Dendrobine 3D分子结构 CAS号:2115-91-5
规格 价格 会员价 库存 数量
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Dendrobine 纯度/质量文件 产品仅供科研

货号:A664519 标准纯度: {[allProObj[0].p_purity_real_show]}
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Dendrobine 生物活性

描述 Dendrobine, a natural product isolated and purified from the herb of Dendrobium nobile Lindl., is an antagonist of β-alanine, taurine and of presynaptic inhibition in the frog spinal cord, has antitumor activity,can inhibit the growth of A549 cells through inducing apoptosis, which is partially dependent on mitochondrial-mediated pathway, and possesses antiviral activity against influenza A viruses, including A/FM-1/1/47 (H1N1), A/Puerto Rico/8/34 H274Y (H1N1), and A/Aichi/2/68 (H3N2) with IC50 values of 3.39 ± 0.32, 2.16 ± 0.91, 5.32 ± 1.68 ug/mL, respectively. Dendrobine treatment decreases mitochondrial membrane potential (MMP), and improves the expression of Bax and inhibited the expression of Bcl-2.

Dendrobine 参考文献

[1]Li R, Liu T, et al. Anti-influenza A Virus Activity of Dendrobine and Its Mechanism of Action. J Agric Food Chem. 2017 May 10;65(18):3665-3674.

[2]Kudo Y, Tanaka A, Yamada K. Dendrobine, an antagonist of beta-alanine, taurine and of presynaptic inhibition in the frog spinal cord. Br J Pharmacol. 1983 Apr;78(4):709-15.

Dendrobine 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.80mL

0.76mL

0.38mL

18.98mL

3.80mL

1.90mL

37.97mL

7.59mL

3.80mL

Dendrobine 技术信息

CAS号2115-91-5
分子式C16H25NO2
分子量 263.375
别名 (–)-Dendrobine
运输蓝冰
存储条件

液体 -20°C:3-6个月-80°C:12个月

粉末 Keep in dark place,Sealed in dry,2-8°C

溶解度

DMSO: 35 mg/mL(132.89 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方
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