规格 | 价格 | 库存 | 数量 |
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快速发货 顺丰冷链运输,1-2 天到达
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描述 | Decanedioic acid, found in royal jelly, is a kind of fatty acids and has many biological activities. In vitro studies, it was found that decanedioic acid had good anti-inflammatory activity in lipopolysaccharide-stimulated RAW 264.7 macrophages model through the inhibition of some special inflammatory cytokines and the regulation of MAPK and NF-κB signaling pathways[1]. Besides this, decanedioic acid only has three to five of the low affinity sites for binding to defatted human plasma albumin[2]. In vivo studies, decanedioic acid could contribute to the improvement of type 2 diabetes in mouse, possibly through increasing the glucose-induced insulin secretion and the inhibition of hepatic glucose output[3]. |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
NCT03234595 | Recurrent High Grade Glioma | Phase 1 Phase 2 | Recruiting | December 31, 2021 | Taiwan ... 展开 >> Hualien Tzu Chi Hospital Recruiting Hualien City, Taiwan, 970 Contact: Jui-Hao Lee, Ph.D. +886-3-863-0108 juihaolee@efbiotech.com 收起 << |
计算器 | ||||
存储液制备 | ![]() | 1mg | 5mg | 10mg |
1 mM 5 mM 10 mM | 4.94mL 0.99mL 0.49mL | 24.72mL 4.94mL 2.47mL | 49.44mL 9.89mL 4.94mL |
CAS号 | 111-20-6 |
分子式 | C10H18O4 |
分子量 | 202.248 |
别名 | 皮脂酸 ;Sebacic acid |
运输 | 蓝冰 |
存储条件 | In solvent -20°C:3-6个月-80°C:12个月 Pure form Sealed in dry,Room Temperature |
溶解方案 | DMSO: 105 mg/mL(519.17 mM),注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO H2O: 1 mg/mL(4.94 mM),配合低频超声,并水浴加热至45℃助溶 以下溶解方案都请先按照体外实验的方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议现用现配,当天使用; 以下溶剂前显示的百分比是指该溶剂在终溶液中的体积占比;如在配制过程中出现沉淀、析出现象,可以通过加热和/或超声的方式助溶
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动物实验配方 |