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Danofloxacin mesylate
甲磺酸达氟沙星 /Danofloxacin mesylate
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货号：A302286
同义名：
CP 76136-27;Danofloxacin (mesylate)
Danofloxacin Mesylate is a fluoroquinolone antibiotic.
Danofloxacin mesylate 化学结构
Danofloxacin mesylate 3D分子结构
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Danofloxacin mesylate 纯度/质量文件 产品仅供科研
货号：A302286
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Danofloxacin mesylate 质控信息
Danofloxacin mesylate 生物活性
描述
Danofloxacin (Mesylate) is a new fluoroquinolone antibacterial, developed specifically for veterinary use. The minimum inhibitory concentration of danofloxacin against 90% (MIC90) of contemporary European and North American field isolates of Pasteurella haemolytica, Pasteurella multocida and Haemophilus somnus, the most important bacterial respiratory pathogens of cattle, was 0.125 micrograms/ml[3] [4]
Danofloxacin mesylate 参考文献
[1] McGuirk PR, Jefson MR, et al. Synthesis and structure-activity relationships of 7-diazabicycloalkylquinolones, including danofloxacin, a new quinolone antibacterial agent for veterinary medicine. J Med Chem. 1992 Feb 21;35(4):611-20.
[2] Giles CJ, Magonigle RA, et al. Clinical pharmacokinetics of parenterally administered danofloxacin in cattle. J Vet Pharmacol Ther. 1991 Dec;14(4):400-10.
[3] Giles CJ, Magonigle RA, Grimshaw WT, Tanner AC, Risk JE, Lynch MJ, Rice JR. Clinical pharmacokinetics of parenterally administered danofloxacin in cattle. J Vet Pharmacol Ther. 1991 Dec;14(4):400-10.
[4] Yang Y, Zhang Y, Li J, Cheng P, Xiao T, Muhammad I, Yu H, Liu R, Zhang X. Susceptibility breakpoint for Danofloxacin against swine Escherichia coli. BMC Vet Res. 2019 Feb 4;15(1):51.
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Danofloxacin mesylate 实验方案
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1mg
5mg
10mg
1 mM
5 mM
10 mM
2.21mL
0.44mL
0.22mL
11.03mL
2.21mL
1.10mL
22.05mL
4.41mL
2.21mL
Danofloxacin mesylate 技术信息
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