规格 | 价格 | 会员价 | 库存 | 数量 | |||
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{[ item.pr_size ]} |
{[ getRatePrice(item.pr_rmb, 1,1) ]} {[ getRatePrice(item.pr_rmb_sale, 1,1) ]} |
{[ getRatePrice(item.pr_rmb, 1,1) ]} {[ getRatePrice(item.pr_rmb,item.pr_rate,1) ]} |
{[ getRatePrice(item.pr_rmb, 1,1) ]} | {[ getRatePrice(item.pr_rmb_sale, 1,1) ]} {[ getRatePrice(item.pr_rmb,item.pr_rate,item.mem_rate) ]} {[ getRatePrice(item.pr_rmb,1,item.mem_rate) ]} | 现货 | 咨询 | - + |
快速发货 顺丰冷链运输,1-2 天到达
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免费溶解
产品名称 | Androgen Receptor ↓ ↑ | 其他靶点 | 纯度 | ||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cyproterone acetate |
++++
Androgen Receptor, IC50: 7.1 nM |
{[allProObj[0].p_purity_real_show]} | |||||||||||||||||
Apalutamide |
+++
Androgen Receptor, IC50: 16 nM |
{[allProObj[0].p_purity_real_show]} | |||||||||||||||||
AZD3514 |
+
Androgen Receptor, Ki: 2.2 μM |
{[allProObj[0].p_purity_real_show]} | |||||||||||||||||
Darolutamide |
++++
Androgen receptor, Ki: 11 nM |
{[allProObj[0].p_purity_real_show]} | |||||||||||||||||
Flutamide |
+++
Androgen Receptor, Ki: 55 nM |
{[allProObj[0].p_purity_real_show]} | |||||||||||||||||
Galeterone |
++
Androgen Receptor, IC50: 384 nM |
{[allProObj[0].p_purity_real_show]} | |||||||||||||||||
Enzalutamide |
+++
Androgen Receptor, IC50: 36 nM |
{[allProObj[0].p_purity_real_show]} | |||||||||||||||||
Megestrol | ✔ | {[allProObj[0].p_purity_real_show]} | |||||||||||||||||
Bicalutamide |
++
Androgen Receptor, IC50: 0.16 μM |
{[allProObj[0].p_purity_real_show]} | |||||||||||||||||
EPI-001 |
+
Androgen Receptor, IC50: ~6 μM |
{[allProObj[0].p_purity_real_show]} | |||||||||||||||||
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多,抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用,但抑制强度暂时没有相关数据。 |
描述 | DJ-V-159 is an agonist of GPRC6A. DJ-V-159 activates ERK in GPRC6A-transfected HEK-293 cells, but has no effect on non-transfected HEK-293 cells, with potency similar to L-Arg. In addition, DJ-V-159 dose-dependently stimulated cAMP production in HEK-293 cells expressing GPRC6A, with a response at a concentration of 0.2 nM in the culture medium. DJ-V-159 stimulated insulin secretion from mouse MIN-6 cells, increasing the insulin stimulation index (SI), with an effect similar to that of Ocn, a known ligand for GPRC6A[1]. |
Animal study | At a dose of 10 mg/kg, injected intraperitoneally, DJ-V-159 reduced blood glucose levels in wild-type mice by 43.6% and 41.9%, 60 and 90 minutes after administration, respectively. |
计算器 | ||||
存储液制备 | ![]() |
1mg | 5mg | 10mg |
1 mM 5 mM 10 mM |
1.99mL 0.40mL 0.20mL |
9.95mL 1.99mL 1.00mL |
19.91mL 3.98mL 1.99mL |
CAS号 | 2253744-53-3 |
分子式 | C24H12F6N4O2 |
分子量 | 502.368 |
别名 | |
运输 | 蓝冰 |
存储条件 |
粉末 Sealed in dry,2-8°C 液体 -20°C:3-6个月-80°C:12个月 |
溶解度 |
DMSO: 25 mg/mL(49.76 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO |
动物实验配方 |