货号:A600380 同义名: RW22164;RWJ22164
Atosiban is competitive antagonist of vasopressin and oxytocin receptors. It is a nonapeptide and the analogue of desamino-oxytocin.
There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.
Type | HazMat fee for 500 gram (Estimated) |
Excepted Quantity | USD 0.00 |
Limited Quantity | USD 15-60 |
Inaccessible (Haz class 6.1), Domestic | USD 80+ |
Inaccessible (Haz class 6.1), International | USD 150+ |
Accessible (Haz class 3, 4, 5 or 8), Domestic | USD 100+ |
Accessible (Haz class 3, 4, 5 or 8), International | USD 200+ |
规格 | 价格 | 会员价 | 库存 | 数量 | |||
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快速发货 顺丰冷链运输,1-2 天到达
品质保证
技术支持
免费溶解
产品名称 | Vasopressin receptor 1 ↓ ↑ | Vasopressin receptor 2 ↓ ↑ | 其他靶点 | 纯度 | |||||||||||||||
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Conivaptan hydrochloride | ✔ | {[allProObj[0].p_purity_real_show]} | |||||||||||||||||
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多,抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用,但抑制强度暂时没有相关数据。 |
描述 | Atosiban is a nonapeptide competitive vasopressin/oxytocin receptor antagonist, and is a desamino-oxytocin analogue. Atosiban inhibits the oxytocin-mediated release of IP3 from the myometrial cell membrane. There is reduced release of intracellular, stored calcium from the sacroplasmic reticulum of myometrial cells, and reduced influx of Ca2+ from the extracellular space through voltage gated channels. In addition, Atosiban suppresses oxytocin-mediated release of PGE and PGF from the decidua[3]. Atosiban resulted in fewer maternal side-effects than nifedipine, with no difference in pregnancy prolongation[4]. |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
NCT00599898 | Labor, Premature | Phase 4 | Completed | - | Israel ... 展开 >> HaEmek Medical Center Afula, Israel, 18100 收起 << |
NCT01796522 | Preterm Delivery. | Phase 3 | Withdrawn(have been published ... 展开 >>new studies that it showed the ineffectiveness of the treatments proposed in this study.) 收起 << | May 2013 | Spain ... 展开 >> Hospital Universitari y Politécnic La Fe Valencia, Spain, 46026 收起 << |
NCT02292784 | Obstetric Labour, Premature | Phase 2 Phase 3 | Recruiting | July 29, 2022 | - |
计算器 | ||||
存储液制备 | 1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
1.01mL 0.20mL 0.10mL |
5.03mL 1.01mL 0.50mL |
10.06mL 2.01mL 1.01mL |
CAS号 | 90779-69-4 |
分子式 | C43H67N11O12S2 |
分子量 | 994.19 |
别名 | RW22164;RWJ22164;Tractocile;ORF 22164;Antocin;Atosiban Acetate |
运输 | 蓝冰 |
存储条件 |
粉末 Keep in dark place,Inert atmosphere,Store in freezer, under -20°C 液体 -20°C:3-6个月-80°C:12个月 |
溶解度 |
DMSO: 16 mg/mL(16.09 mM),注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO H2O: 15 mg/mL(15.09 mM),配合低频超声助溶 |
动物实验配方 |