Acyclovir is a highly potent inhibitor of herpes simplex virus (HSV), types 1 and 2, and varicella zoster virus as it is an acrylic purine nucleoside analog.
Acyclovir (aciclovir) is a nucleoside antiviral drug with antiviral activity in vitro against members of the herpes group of DNA viruses. As an established treatment of herpes simplex infection, intravenous, oral and to a lesser extent topical formulations of acyclovir provide significant therapeutic benefit in genital herpes simplex and recurrent orofacial herpes simplex. Ophthalmic application of 3% acyclovir ointment rapidly heals herpetic dendritic corneal ulcers and superficial herpetic keratitis[3]. Acyclovir is a selective antiherpes agent. Its selective activity is by exploitation of differences between the herpes-specific and host cell enzymes. In immunocompromised patients, acyclovir is effective for the prophylaxis and therapy of herpes simplex virus infections and for the treatment of herpes zoster and varicella. In nonimmunocompromised patients, acyclovir is beneficial in the therapy of herpes keratoconjunctivitis and in the therapy of genital herpes, with maximal benefit seen in those patients who have primary genital herpes[4]. Acyclovir (aciclovir) is a nucleoside analogue antiviral drug related to cytarabine, idoxuridine, trifluridine and vidarabine. Orally and intravenously administered acyclovir were beneficial in initial genital herpes infections, and oral therapy shortened the duration of recurrent infections by 1 to 2 days but did not ameliorate pain[5].
Acyclovir 细胞研究
细胞系
浓度
检测类型
检测时间
活动说明
数据源
African green monkey Vero 76 cells
Cytotoxicity assay
48-96 h
Cytotoxicity against African green monkey Vero 76 cells assessed as cell viability after 48 to 96 hrs by crystal violet staining, CC50=13 μM
26119992
african green monkey Vero cells
Function assay
48 h
Antiviral activity against HSV2 strain 333 infected in african green monkey Vero cells assessed as inhibition of cytopathic effect after 48 hrs by plaque reduction assay, EC50=1.87 μM
22704890
BSC-1 cells
Function assay
Antiviral activity of the compound was evaluated against the Herpes simplex virus type-1 in BSC-1 cells, IC50=2.6 μM
2913300
BSC-1 cells
Function assay
Effective concentration required to inhibit herpes simplex virus 1 in BSC-1 cells in ELISA, EC50=1.5 μM
Cytotoxicity against African green monkey Vero 76 cells assessed as cell viability after 48 to 96 hrs by crystal violet staining, CC50=13 μM
26119992
african green monkey Vero cells
Function assay
48 h
Antiviral activity against HSV2 strain 333 infected in african green monkey Vero cells assessed as inhibition of cytopathic effect after 48 hrs by plaque reduction assay, EC50=1.87 μM
22704890
BSC-1 cells
Function assay
Antiviral activity of the compound was evaluated against the Herpes simplex virus type-1 in BSC-1 cells, IC50=2.6 μM
2913300
BSC-1 cells
Function assay
Effective concentration required to inhibit herpes simplex virus 1 in BSC-1 cells in ELISA, EC50=1.5 μM
15634003
Daudi cells
Function assay
Inhibition of EBV replication in Daudi cells by viral capsid antigen-ELISA, EC50=0.33 μM
17004726
HEL cell
Function assay
Effective concentration required to inhibit Tyrosine kinase (TK+) Varicella-Zoster virus-induced cytopathicity by 50% in OKA strain HEL cell lines, EC50=4.53 μM
11495586
HEL cells
Function assay
Compound was tested for anti-viral activity against HSV-1(G) in HEL cells, EC50=1.3 μM
14643328
HEL cells
Function assay
4 days
Antiviral activity against HSV1 KOS infected in HEL cells assessed as inhibition of virus-induced cytopathogenicity after 4 days, EC50=0.2 μM
22459876
HEL cells
Function assay
Antiviral activity against HSV1 KOS infected in HEL cells assessed as inhibition of virus-induced cytopathic effect, EC50=0.14 μM
23099097
HeLa cell
Function assay
Ability to inhibit cytopathogenicity of herpes simplex type 1 virus (G) in HeLa cell culture, IC50=0.19 μM
11356110
HeLa cells
Function assay
Inhibition of HSV-1 DNA synthesis in virus-infected HeLa cells, IC50=1.9 μM
7752206
HEp-2 cells
Function assay
Minimum inhibitory concentration causing 25% inhibition of cytopathic effect induced by Herpes simplex virus-1 (K979) in HEp-2 cells
2842506
HFF cells
Function assay
Concentration for HSV-1 plaque reduction (VPR) by 50% in HFF cells, EC50=1.1 μM
14584954
HFF cells
Function assay
Inhibitory concentration required to reduce HSV-1 induced cytopathogenic effect (CPE) by 50 % in HFF cells, EC50=2.22 μM
14584954
HFF cells
Function assay
Effective concentration required to inhibit varicella zoster virus replication in HFF cells, EC50=1.6 μM
15634003
HFF cells
Function assay
Effective concentration required to inhibit herpes simplex virus 1 in HFF cells in cytopathic effect (CPE) assay, EC50=0.9 μM
15634003
HSV-1 E-377 Vero cells
Function assay
Inhibition of plaque formation in monolayers of HSV-1 E-377 Vero cells by 50%, EC50=4.4 μM
11585457
HSV-1 KOS Vero cells
Function assay
Inhibition of plaque formation in monolayers of HSV-1 KOS Vero cells by 50%, EC50=2.2 μM
11585457
HSV-2 MS Vero cells
Function assay
Inhibition of viral cytopathic effect in infected human foreskin fibroblast cell monolayers of HSV-2 MS Vero cells by 50%, EC50=6.2 μM
11585457
human embryonic lung cells
Function assay
Antiviral activity was measured as effective concentration required to reduce Varicella Zoster virus (OKA)-induced plaque formation in human embryonic lung cells, EC50=1.1 μM
11549457
human HFF cells
Function assay
Inhibitory concentration of the drug against the cytopathic effect for E-377 strain of herpes simplex virus-1 (HSV-1) in human HFF cells, EC50=0.04 μM
8394933
human HFF cells
Function assay
Inhibitory concentration of the drug against the cytopathic effect for MS strain of herpes simplex virus-2 (HSV-2) in human HFF cells, EC50=0.09 μM
8394933
human lung fibroblasts (MRC-5)
Function assay
Compound was tested for antiviral activity against Herpes Simplex virus Type-1(18189) in human lung fibroblasts (MRC-5)
3040998
MRC-5 cells
Function assay
Antiviral activity in plaque reduction assay was determined against herpes simplex virus type 2 (HSV-2) in MRC-5 cells, IC50=2.5 μM
2153202
P3HR-1 cells
Function assay
Effective concentration for the inhibition of Epstein-Barr virus EBV-DNA synthesis in human lymphoblastoid P3HR-1 cells, EC50=6.75 μM
12408726
Raji cells
Function assay
Inhibitory concentration of the drug against the antigen production against P3HR-1 strain of epstein barr virus-2 (EBV) in Raji cells, EC50=2.9 μM
8394933
Vero cells
Function assay
Inhibitory activity against herpes simplex virus type 2 (HSV 2) strain 186 in Vero cells, IC50=1.7 μM
8576922
WI-38 cell
Function assay
Anti viral activity against VZV(pplla strain) in WI-38 cell monolayers, ID50=4 μM
Slovenia
... 展开 >> Department of Infectious Diseases, University Medical Center Ljubljana, Ljubljana, Slovenia
Recruiting
Ljubljana, Slovenia, 1525
Contact: Daša Stupica, MD +386 1 522 2110 dasa.stupica@kclj.si
Contact: Franc Strle, MD +386 1 5222610 franc.strle@kclj.si
Principal Investigator: Daša Stupica, MD
Sub-Investigator: Franc Strle, MD
UMC Ljubljana, Department of Infectious Diseases
Recruiting
Ljubljana, Slovenia, 1525
Contact: Daša Stupica, MD, PhD +386 1 522 2110 dasa.stupica@kclj.si
Contact: Franc Strle, MD, PhD +386 1 522 2610 franc.strle@kclj.si 收起 <<
United States, Alabama
... 展开 >>
GSK Investigational Site
Birmingham, Alabama, United States, 35233
United States, Arkansas
GSK Investigational Site
Little Rock, Arkansas, United States, 72202
United States, California
GSK Investigational Site
San Diego, California, United States, 92123
United States, Florida
GSK Investigational Site
Jacksonville, Florida, United States, 32209
United States, Kentucky
GSK Investigational Site
Lexington, Kentucky, United States, 40503
GSK Investigational Site
Louisville, Kentucky, United States, 40202
United States, Louisiana
GSK Investigational Site
New Orleans, Louisiana, United States, 70112
United States, North Carolina
GSK Investigational Site
Durham, North Carolina, United States, 27705
United States, Ohio
GSK Investigational Site
Cincinnati, Ohio, United States, 45229
United States, Texas
GSK Investigational Site
Galveston, Texas, United States, 77555-0653
Chile
GSK Investigational Site
Santiago, Región Metro De Santiago, Chile, 7580206
South Africa
GSK Investigational Site
Brits, South Africa, 2000
GSK Investigational Site
George, South Africa, 6529 收起 <<
United States, Pennsylvania
... 展开 >>
Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, United States, 19104
United States, Texas
Texas Children's Hospital
Houston, Texas, United States, 77030 收起 <<
Metastatic Castration-resistan... 展开 >>t Prostate Cancer 收起 <<
Phase 2
Completed
-
United States, Alabama
... 展开 >>
Birmingham VA Medical Center
Birmingham, Alabama, United States, 35233
University of Alabama at Birmingham
Birmingham, Alabama, United States, 35294
United States, Georgia
Cancer Life Center, Navicent Health
Macon, Georgia, United States, 31210
United States, Louisiana
University of Tulane
New Orleans, Louisiana, United States, 70118 收起 <<
United States, California
... 展开 >>
City of Hope Comprehensive Cancer Center
Duarte, California, United States, 91010-3000
Stanford Cancer Center at Stanford University Medical Center
Stanford, California, United States, 94305
United States, Nebraska
UNMC Eppley Cancer Center at the University of Nebraska Medical Center
Omaha, Nebraska, United States, 68198-3330
United States, Texas
Baylor University Medical Center
Dallas, Texas, United States, 75246
United States, Utah
Huntsman Cancer Institute
Salt Lake City, Utah, United States, 84132
United States, Washington
Fred Hutchinson Cancer Research Center
Seattle, Washington, United States, 98109-1024 收起 <<
United States, New Jersey
... 展开 >>
Memoral Sloan Kettering Cancer Center
Basking Ridge, New Jersey, United States
United States, New York
Memorial Sloan Kettering Cancer Center @ Suffolk
Commack, New York, United States, 11725
Memorial Sloan Kettering Cancer Center
New York, New York, United States, 10065
Memorial Sloan Kettering Cancer Center at Mercy Medical Center
Rockville Centre, New York, United States, 11570
Memoral Sloan Kettering Cancer Center at Phelps
Sleepy Hollow, New York, United States, 10591 收起 <<
United States, California
... 展开 >>
Mem Med Group Inc
Long Beach, California, United States, 90806
AIDS Healthcare Foundation Labs
Los Angeles, California, United States, 90027
Sharp Mission Park / Med Group
Oceanside, California, United States, 92054
Park Ctr for Health / Keith Vrhel
San Diego, California, United States, 92103
Potrero Hill Med Ctr
San Francisco, California, United States, 94107
HIV Primary Care & Consult
Santa Rosa, California, United States, 95404
United States, Florida
Central Florida Research Initiative
Maitland, Florida, United States, 32751
United States, Georgia
Braude Mermin Spivey MD PC
Atlanta, Georgia, United States, 30309
United States, Illinois
Christie Clinic / Urbana Campus
Urbana, Illinois, United States, 61801
United States, Massachusetts
Heywood Memorial Hosp
Gardner, Massachusetts, United States, 01440
United States, New York
Gouverneur Hosp
New York, New York, United States, 10002
United States, Texas
Central Texas Med Foundation
Austin, Texas, United States, 78751
Dr Nicholaos Bellos
Dallas, Texas, United States, 75225
Dr Susan M Diamond
Dallas, Texas, United States, 75225
ID Associates
Dallas, Texas, United States, 75231 收起 <<
United States, New York
... 展开 >>
New York University School of Medicine
Not yet recruiting
New York, New York, United States, 10016
Contact: Stacy Mach 929-455-5539 Stacy.Mach@nyumc.org
Principal Investigator: Leela Raju, MD 收起 <<
United States, California
... 展开 >>
Francis I. Proctor Foundation, University of California, San Francisco
San Francisco, California, United States
United States, Georgia
Emory Eye Center
Atlanta, Georgia, United States
United States, Illinois
Eye Center, University of Illinois, Chicago
Chicago, Illinois, United States
United States, Louisiana
Louisiana State University Eye Center
New Orleans, Louisiana, United States
United States, New York
Department of Ophthalmology, The Mount Sinai Medical Center
New York, New York, United States
United States, Pennsylvania
Wills Eye Hospital, Cornea Clinic
Philadelphia, Pennsylvania, United States
United States, Texas
Cullen Eye Institute, Baylor College of Medicine
Houston, Texas, United States
United States, Wisconsin
The Eye Institute, Medical College of Wisconsin
Milwaukee, Wisconsin, United States 收起 <<
United States, Arizona
... 展开 >>
Scottsdale, Arizona, United States, 85251
United States, California
Santa Rosa, California, United States, 95405
United States, Florida
Pinellas Park, Florida, United States, 33781
United States, Minnesota
Edina, Minnesota, United States, 55435
United States, Missouri
Saint Louis, Missouri, United States, 63141
United States, Ohio
Akron, Ohio, United States, 44311
Cincinnati, Ohio, United States, 45236
United States, South Carolina
Anderson, South Carolina, United States, 29621
Greer, South Carolina, United States, 29650
United States, Texas
San Antonio, Texas, United States, 78229 收起 <<
Botswana
... 展开 >> Botswana-Harvard Partnership
Gabarone, Botswana
Kenya
Moi University - Indiana University
Eldoret, Kenya
Kemri - Ucsf
Kisumu, Kenya
University of Nairobi
Nairobi, Kenya
Partners Study Thika Site
Thika, Kenya
Rwanda
Projet San Francisco-Emory University
Kigali, Rwanda
South Africa
University of Cape Town
Cape Town, South Africa
Perinatal HIV Research Unit, University of Witswatersrand
Johannesburg, South Africa
Reproductive Health and HIV Research Unit
Johannesburg, South Africa
Tanzania
Kilimanjaro Christian Medical College-Harvard University
Moshi, Tanzania
Uganda
Mulago Hospital - IDI
Kampala, Uganda
Zambia
Zambia-Emory HIV Research Project
Lusaka, Zambia
Zambia-Emory HIV Research Project
Ndola/Kitwe, Zambia 收起 <<
United States, California
... 展开 >>
UCLA CARE Ctr
Los Angeles, California, United States, 90095
Huntington Memorial Hosp
Pasadena, California, United States, 91105 收起 <<
United States, California
... 展开 >>
Ucsf Aids Crs
San Francisco, California, United States
United States, Colorado
University of Colorado Hospital CRS
Aurora, Colorado, United States
United States, Illinois
Cook County Hosp. CORE Ctr.
Chicago, Illinois, United States
Northwestern University CRS
Chicago, Illinois, United States
Rush Univ. Med. Ctr. ACTG CRS
Chicago, Illinois, United States
United States, Maryland
Johns Hopkins Adult AIDS CRS
Baltimore, Maryland, United States, 21287
United States, Missouri
Washington U CRS
St. Louis, Missouri, United States
United States, New York
NY Univ. HIV/AIDS CRS
New York, New York, United States, 10016 收起 <<
United States, California
... 展开 >>
UCSF - San Francisco Gen Hosp
San Francisco, California, United States, 94110
United States, Florida
TheraFirst Med Ctrs Inc
Fort Lauderdale, Florida, United States, 33308
United States, New York
Saint Luke's - Roosevelt Hosp Ctr
New York, New York, United States, 10025
United States, Utah
Univ of Utah School of Medicine
Salt Lake City, Utah, United States, 84132 收起 <<
United States, California
... 展开 >>
CARE Ctr / UCLA Med Ctr
Los Angeles, California, United States, 90095
United States, District of Columbia
George Washington Univ Med Ctr
Washington, District of Columbia, United States, 20037
United States, Florida
South Miami Hosp
Miami, Florida, United States, 33143
United States, Illinois
Dr Thomas Klein
Chicago, Illinois, United States, 60610
United States, New York
Bellevue Hosp Ctr
New York, New York, United States, 10016
United States, Ohio
Univ Hosps of Cleveland
Cleveland, Ohio, United States, 44106
United States, Rhode Island
Roger Williams Med Ctr
Providence, Rhode Island, United States, 02908
United States, Wisconsin
Milwaukee County Med Complex
Milwaukee, Wisconsin, United States, 53226 收起 <<
United States, Connecticut
... 展开 >>
Yale University School of Medicine - Infectious Diseases
Recruiting
New Haven, Connecticut, United States, 06510
Contact: Rodolfo N. Molina, M.D. 203-785-7031 Rodolfo.molina@yale.edu
United States, District of Columbia
Geogetown University Hospital
Recruiting
Washington, District of Columbia, United States, 20007
Contact: Maximiliano Menna 202-444-0371 mpm229@georgetown.edu
United States, Florida
Midway Immunology and Research Center (MIRC)
Recruiting
Fort Pierce, Florida, United States, 34982
Contact: Carly Sharp 772-595-9830 info@midwayresearch.com
Comprehensive Care Center dba Community AIDs Network
Recruiting
Sarasota, Florida, United States, 34237
Contact: Angela Ristuccia 941-366-0134 ext 11122 aristuccia@cancommunityhealth.org
United States, Georgia
Emory Hospital Midtown Infectious Disease Clinic
Recruiting
Atlanta, Georgia, United States, 30308
Contact: Joan Lopez 404-686-5198 jllopez@emory.edu
United States, Illinois
Northwestern University
Recruiting
Chicago, Illinois, United States, 60611
Contact: Meredith Marshall 312-926-1076 meredith.marshall@northwestern.edu
Department of Medicine J. H. Stroger Hospital of Cook County
Recruiting
Chicago, Illinois, United States, 60612
Contact: Mieoak Bahk 312-572-4543 mbahk@cookcountyhhs.org
University of Chicago
Recruiting
Chicago, Illinois, United States, 60637
Contact: Jennifer Theusch 773-702-1665 jtheusch@medicine.bsd.uchicago.edu
United States, Indiana
Indiana University (IU) Infectious Diseases Research
Recruiting
Indianapolis, Indiana, United States, 46202
Contact: Paula Johnson 317-274-8473 johnpaul@iu.edu
United States, Louisiana
LSU Health Baton Rouge Pulmonary Clinic
Recruiting
Baton Rouge, Louisiana, United States, 70809
Contact: Jennifer Daigle 225-757-4150 jdai11@lsuhsc.edu
United States, Maryland
John Hopkins University School of Medicine
Recruiting
Baltimore, Maryland, United States, 21287
Contact: Oyinkan Kusemiju 410-614-0648 Okusemi1@jhmi.edu
United States, Massachusetts
Massachusetts General Hospital
Recruiting
Boston, Massachusetts, United States, 02114
Brigham and Women's Hospital
Recruiting
Boston, Massachusetts, United States, 02115
Contact: Nicolas Issa 617-525-8418 NISSA@BWH.HARVARD.EDU
United States, Michigan
Wayne State University
Recruiting
Detroit, Michigan, United States, 48201
Henry Ford Health System
Recruiting
Detroit, Michigan, United States, 48202
Contact: Katelyn Clark 313-916-2613 kclark7@hfhs.org
United States, New York
SUNY Downstate Medical Center
Recruiting
Brooklyn, New York, United States, 11203
Contact: Michael Augenbraun 718-270-1432 Michael.Augenbraun@downstate.edu
United States, Texas
MD Anderson Cancer Center
Recruiting
Houston, Texas, United States, 77030-4009
Contact CR_Study_Registration@mdanderson.org
United States, Washington
Fred Hutchinson Cancer Research Center
Recruiting
Seattle, Washington, United States, 98109 收起 <<
United States, Illinois
... 展开 >>
Rush Univ. Med. Ctr. ACTG CRS
Chicago, Illinois, United States, 60612
United States, Massachusetts
Beth Israel Deaconess - East Campus A0102 CRS
Boston, Massachusetts, United States, 02215
United States, New York
Univ. of Rochester ACTG CRS
Rochester, New York, United States
United States, Washington
University of Washington AIDS CRS
Seattle, Washington, United States, 98105 收起 <<
United States, Alabama
... 展开 >>
Birmingham Veterans Administration Med Ctr / Univ of Alabama
Birmingham, Alabama, United States, 35233
United States, Arizona
Univ of Arizona / Health Science Ctr
Tucson, Arizona, United States, 85724
United States, California
ViRx Inc
San Francisco, California, United States, 94103
United States, District of Columbia
Georgetown Univ Med Ctr / Main Hosp 4
Washington, District of Columbia, United States, 20007
United States, Florida
Veterans Administration Med Ctr
Bay Pines, Florida, United States, 33504
United States, Illinois
Rush Presbyterian - Saint Luke's Med Ctr
Chicago, Illinois, United States, 60612
United States, Michigan
Harper Hosp
Detroit, Michigan, United States, 48201
United States, Pennsylvania
Univ of Pennsylvania / HIV Clinic
Philadelphia, Pennsylvania, United States, 19104
United States, Tennessee
Vanderbilt School of Medicine
Nashville, Tennessee, United States, 37232
United States, Texas
Univ TX Galveston Med Branch
Galveston, Texas, United States, 77550
Baylor College of Medicine
Houston, Texas, United States, 77030
United States, Utah
Univ of Utah School of Medicine
Salt Lake City, Utah, United States, 84132
United States, Virginia
Univ of Virginia Health Sciences Ctr
Charlottesville, Virginia, United States, 22908
Richmond AIDS Consortium
Richmond, Virginia, United States, 23219 收起 <<
United States, Massachusetts
... 展开 >>
Bmc Actg Crs
Boston, Massachusetts, United States, 02118
Beth Israel Deaconess - East Campus A0102 CRS
Boston, Massachusetts, United States, 02215
Beth Israel Deaconess Med. Ctr., ACTG CRS
Boston, Massachusetts, United States, 02215
Massachusetts General Hospital ACTG CRS
Worcester, Massachusetts, United States, 01655
United States, Minnesota
University of Minnesota, ACTU
Minneapolis, Minnesota, United States, 55455
United States, North Carolina
Unc Aids Crs
Chapel Hill, North Carolina, United States, 27599
Regional Center for Infectious Disease, Wendover Medical Center CRS
Greensboro, North Carolina, United States, 27401
United States, Washington
University of Washington AIDS CRS
Seattle, Washington, United States, 98122 收起 <<
United States, California
... 展开 >>
Los Angeles County - USC Med Ctr
Los Angeles, California, United States, 90033
Univ of California / San Diego Treatment Ctr
San Diego, California, United States, 921036325
United States, Washington
Univ of Washington
Seattle, Washington, United States, 98105 收起 <<
Cytomegalovirus Retinitis
... 展开 >> HIV Infections 收起 <<
Not Applicable
Completed
-
United States, Illinois
... 展开 >>
Northwestern Univ Med School
Chicago, Illinois, United States, 60611
Rush Presbyterian - Saint Luke's Med Ctr
Chicago, Illinois, United States, 60612 收起 <<
United States, Alabama
... 展开 >>
Radiant Research Birmingham
Birmingham, Alabama, United States, 35209
United States, California
Radiant Research Santa Rosa
Santa Rosa, California, United States, 95405
United States, Florida
Radiant Research St. Petersburg
Pinellas Park, Florida, United States, 33781
United States, Illinois
Radiant Research Chicago
Chicago, Illinois, United States, 60610
United States, Minnesota
Radiant Research Minneapolis
Edina, Minnesota, United States, 55435
United States, Missouri
Radiant Research St. Louis
St. Louis, Missouri, United States, 63141
United States, New York
Rochester Clinical Research, Inc.
Rochester, New York, United States, 14609
United States, Ohio
Radiant Research Cincinnati
Cincinnati, Ohio, United States, 45236
Radiant Research Akron
Mogadore, Ohio, United States, 44260
United States, Rhode Island
OMEGA Medical Research
Warwick, Rhode Island, United States, 02886
United States, South Carolina
Radiant Research Greer
Greer, South Carolina, United States, 29651
United States, Texas
Radiant Research Dallas North
Dallas, Texas, United States, 75231
Radiant Research San Antonio
San Antonio, Texas, United States, 78229 收起 <<
United States, California
... 展开 >>
AIDS Research Ctr
Palo Alto, California, United States, 94304
Harbor-UCLA Med Ctr
Torrance, California, United States, 90502
United States, Connecticut
Yale Univ School of Medicine / AIDS Program
New Haven, Connecticut, United States, 06510
United States, Florida
North Broward Hosp District
Fort Lauderdale, Florida, United States, 33316
Univ of Miami / Jackson Memorial Hosp
Miami, Florida, United States, 331361094
United States, Illinois
Univ of Illinois - Chicago
Chicago, Illinois, United States, 60612
Univ of Illinois Chicago / Howard Brown Hlth Ctr
Chicago, Illinois, United States, 60612
United States, Maryland
Johns Hopkins Univ
Baltimore, Maryland, United States, 21205
United States, New York
SUNY Brooklyn / SUNY Health Sciences Ctr at Brooklyn
Brooklyn, New York, United States, 11203
Community Research Initiative on AIDS
New York, New York, United States, 10001
NYU - Bellevue Hosp
New York, New York, United States, 10016
New York Med College / Westchester County Med Ctr
Valhalla, New York, United States, 10595
United States, Oregon
Research and Education Group
Portland, Oregon, United States, 97210
United States, Pennsylvania
Univ of Pennsylvania Med Ctr
Philadelphia, Pennsylvania, United States, 19104
United States, Rhode Island
Brown Univ / The Miriam Hosp
Providence, Rhode Island, United States, 02906 收起 <<
United States, California
... 展开 >>
MCS Clinical Trials
Los Angeles, California, United States, 90057
United States, Florida
Sunshine Research Center
Opa-Locka, Florida, United States, 33054
Altus Rsearch,INC
West Palm Beach, Florida, United States, 33407
United States, Illinois
Provident Clincal Research
Addison, Illinois, United States, 60101
United States, Kentucky
Central Kentucky Research
Lexington, Kentucky, United States, 40509
United States, New York
Rochester Clinical Research
Rochester, New York, United States, 14609
United States, North Carolina
PGM Research of Winston-Salem, LLC
Winston-Salem, North Carolina, United States, 27103
United States, Rhode Island
Clinical Partners LLC
Johnston, Rhode Island, United States, 02919
United States, Texas
Corsicana Medical Research,PNC
Corsicana, Texas, United States, 75110
United States, Virginia
National Clinical Research-Richmond,Inc.
Richmond, Virginia, United States, 23294 收起 <<
HIV Infections
... 展开 >> HIV Seronegativity
Herpes Genitalis 收起 <<
Phase 3
Completed
-
United States, California
... 展开 >>
San Francisco Department of Public Health, AIDS Office, Research Section
San Francisco, California, United States, 94102
United States, New York
New York Blood Center
New York City, New York, United States
United States, Washington
University of Washington
Seattle, Washington, United States, 98104 收起 <<
HIV Infections
... 展开 >> Ulcer
Herpes Simplex 收起 <<
Phase 2
Phase 3
Completed
-
South Africa
... 展开 >> Eloff Street Clinic
Johannesburg, Gauteng, South Africa
Green Door, Alexandra Health Centre
Johannesburg, Gauteng, South Africa 收起 <<
Brazil
... 展开 >> Centro de Medicina Reprodutiva Dr Carlos Isaia Filho Ltda
Porto Alegre, RS, Brazil
Hospital de Clínicas de Porto Alegre
Porto Alegre, RS, Brazil
SPVita
Braganca Paulista, SP, Brazil
Caep Centro Avancado de Estudos E Pesquisas Ltda
Campinas, SP, Brazil
CEMICAMP - Centro de Pesquisas em Saúde Reprodutiva de Campinas
Campinas, SP, Brazil
CECIP - Centro de Estudos Clínicos do Interior Paulista
Jau, SP, Brazil
Hospital das Clínicas da Faculdade de Medicina de Ribeirao Preto da Universidade de Sao Paulo
Ribeirao Preto, SP, Brazil, 14048900
Instituto Sirio Libanes de Ensino e Pesquisa
Sao Paulo, SP, Brazil, 01308-060
Afip - Associacao Fundo de Incentivo A Psicofarmacologia
Sao Paulo, SP, Brazil 收起 <<
United States, North Carolina
... 展开 >>
Wake Forest University Comprehensive Cancer Center
Winston-Salem, North Carolina, United States, 27157-1096 收起 <<
Brazil
... 展开 >> Centro de Medicina Reprodutiva Dr Carlos Isaia Filho
Recruiting
Porto Alegre, RS, Brazil
Contact: Carlos Isaia Filho, MD 55 51 3222-8180
Principal Investigator: Carlos Isaia Filho, MD
Loema
Recruiting
Campinas, SP, Brazil, 13010001
Contact: Fabio R Santos, MD contato@loemaipc.com.br
Principal Investigator: Fabio R Santos, MD
CECIP Centro de Estudos Clínicos do Interior Paulista
Recruiting
Jau, SP, Brazil
Contact: Paula U. Tokunaga, MD cecipjau@gmail.com
Principal Investigator: Paula U. Tokunaga, MD
Afip - Associacao Fundo de Incentivo A Pesquisa
Recruiting
Sao Paulo, SP, Brazil
Contact: Jane Tomimori, MD 55 11 5908 7081
Principal Investigator: Jane Tomimori, MD
Allergisa
Recruiting
Campinas, São Paulo, Brazil
Contact: Andre L Vergnanini, MD +55193789-8600
Principal Investigator: André L Vergnanini, MD 收起 <<
United States, Kansas
... 展开 >>
Wesely Medical Center
Wichita, Kansas, United States, 67214-4976
United States, Louisiana
Tulane School of Medicine
New Orleans, Louisiana, United States, 70112
United States, North Carolina
Duke University
Durham, North Carolina, United States, 27713 收起 <<
United States, West Virginia
... 展开 >>
West Virginia University Hospitals
Recruiting
Morgantown, West Virginia, United States, 26506
Contact: Pam Bunner 304-598-4511 bunnerp@wvumedicine.org 收起 <<
United States, West Virginia
... 展开 >>
West Virginia University Hospitals Mary Babb Randolph Cancer Center
Morgantown, West Virginia, United States, 26506 收起 <<
South Africa
... 展开 >> Reproductive Health and HIV Research Unit (RHRU)
Johannesburg, South Africa
Zambia
Center for Infectious Disease Research of Zambia (CIDRZ)
Lusaka, Zambia 收起 <<
Vulvar Cancer
... 展开 >> Vulvar Intraepithelial Neoplasia 收起 <<
Phase 2
Completed
-
Switzerland
... 展开 >> Institute for Applied Nursing Sciences IPW, University of Applied Sciences FHS St. Gallen, Switzerland
St. Gallen, Switzerland, 9001 收起 <<
United States, Michigan
... 展开 >>
Karmanos Cancer Institute
Detroit, Michigan, United States, 48201
United States, Ohio
UPMC Cancer Centers - Teramana Cancer Center
Steubenville, Ohio, United States, 43952
United States, Pennsylvania
UPMC Cancer Centers - Beaver
Beaver, Pennsylvania, United States, 15009
UPMC Cancer Centers - Jefferson
Clairton, Pennsylvania, United States, 15025
UPMC Cancer Centers - Arnold Palmer at Mountain View
Greensburg, Pennsylvania, United States, 15601
UPMC Cancer Centers - Arnold Palmer at Oakbrook
Greensburg, Pennsylvania, United States, 15601
UPMC Cancer Centers - Indiana
Indiana, Pennsylvania, United States, 15701
UPMC Cancer Centers - Johnstown
Johnstown, Pennsylvania, United States, 15901
Hematology-Oncology Associates of UPCI
McKeesport, Pennsylvania, United States, 15132
Hematology/Oncology - Private Practice
McKeesport, Pennsylvania, United States, 15132
UPMC Cancer Centers - Monroeville
Monroeville, Pennsylvania, United States, 15146
UPMC Cancer Centers - Arnold Palmer at Mt. Pleasant
Mount Pleasant, Pennsylvania, United States, 15666
UPMC Cancer Centers - New Castle
New Castle, Pennsylvania, United States, 16105
UPMC Cancer Centers - St. Margaret's
Pittsburgh, Pennsylvania, United States, 15215
UPMC Cancer Centers - Hillman Cancer Center
Pittsburgh, Pennsylvania, United States, 15232
UPMC Cancer Centers - Passavant
Pittsburgh, Pennsylvania, United States, 15237
VA Healthcare System - 646
Pittsburgh, Pennsylvania, United States, 15240
UPMC Cancer Centers - Drake
Pittsburgh, Pennsylvania, United States, 15241
UPMC Cancer Centers - Uniontown
Uniontown, Pennsylvania, United States, 15401
UPMC Cancer Centers - Washington
Washington, Pennsylvania, United States, 15301
UPMC Cancer Centers - North Hills
Wexford, Pennsylvania, United States, 15090
UPMC Cancer Centers - Windber
Windber, Pennsylvania, United States, 15963 收起 <<
United States, Alabama
... 展开 >>
Lurleen Wallace Comprehensive Cancer at University of Alabama-Birmingham
Birmingham, Alabama, United States, 35294
University of Alabama at Birmingham Comprehensive Cancer Center
Birmingham, Alabama, United States, 35294
United States, California
Jonsson Comprehensive Cancer Center at UCLA
Los Angeles, California, United States, 90095
University of California San Francisco Medical Center
San Francisco, California, United States, 94143
United States, Maryland
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Baltimore, Maryland, United States, 21231
United States, Massachusetts
Massachusetts General Hospital Cancer Center
Boston, Massachusetts, United States, 02114
Dana Farber Cancer Institute
Boston, Massachusetts, United States, 02215
United States, Michigan
Henry Ford Hospital
Detroit, Michigan, United States, 48202
Josephine Ford Cancer Center at Henry Ford Hospital
Detroit, Michigan, United States, 48202
United States, New York
Memorial Sloan-Kettering Cancer Center
New York, New York, United States, 10021
United States, North Carolina
Wake Forest University Comprehensive Cancer Center
Winston-Salem, North Carolina, United States, 27157
United States, Ohio
Cleveland Clinic Taussig Cancer Center
Cleveland, Ohio, United States, 44195
United States, Pennsylvania
Abrams Cancer Center of the University of Pennsylvania
Philadelphia, Pennsylvania, United States, 19104
Hillman Cancer Center at University of Pittsburgh Cancer Institute
Pittsburgh, Pennsylvania, United States, 15232 收起 <<
United States, Kentucky
... 展开 >>
Primary Care Centers of East Kentucky
Recruiting
Hazard, Kentucky, United States, 41701
Contact: Jing Li jingli.tj@uky.edu
Lewis County Primary Care Center, Inc.
Recruiting
Vanceburg, Kentucky, United States, 41179
Contact: Jing Li jingli.tj@uky.edu
United States, Minnesota
Mayo Clinic in Rochester
Recruiting
Rochester, Minnesota, United States, 55905
Contact: Emma M. Behnken 507-293-0177 Behnken.Emma@mayo.edu
Mayo Health System - Springfield
Recruiting
Springfield, Minnesota, United States, 56087
Contact: Kelsey Nylander, D.O. 507-723-6207
United States, North Carolina
Vidant Multispecialty Clinic Belhaven
Recruiting
Belhaven, North Carolina, United States, 27810
Contact: Paul Bray pbray@vidanthealth.com
Elizabeth Family Medicine
Recruiting
Charlotte, North Carolina, United States, 28207
Contact: Brisa Hernandez Brisa.Hernandez@carolinashealthcare.org
CMC- Union Family Medicine
Recruiting
Charlotte, North Carolina, United States, 28208
Contact: Brisa Hernandez Brisa.Hernandez@carolinashealthcare.org
Vidant Family Medicine Chocowinity
Recruiting
Chocowinity, North Carolina, United States, 28717
Contact: Paul Bray 252-717-4402 pbray@vidanthealth.com
United States, Wisconsin
Mayo Clinic Health System La Crosse
Recruiting
La Crosse, Wisconsin, United States, 54601
Contact: Kristen Dall-Winther, MD 收起 <<
United States, California
... 展开 >>
VA San Diego Healthcare System, San Diego, CA
San Diego, California, United States, 92161
VA Greater Los Angeles Healthcare System, West Los Angeles, CA
West Los Angeles, California, United States, 90073
United States, Nevada
VA Southern Nevada Healthcare System, North Las Vegas, NV
Las Vegas, Nevada, United States, 89106 收起 <<
China
... 展开 >> Beijing Children's Hospital of Capital Medical University
Recruiting
Beijing, China
Contact: Adong Shen, Master 13370115087 shenad16@hotmail.com 收起 <<
United States, Louisiana
... 展开 >>
LSU Eye Center
Recruiting
New Orleans, Louisiana, United States, 70112
Children's Hospital
Recruiting
New Orleans, Louisiana, United States, 70118
Principal Investigator: Herbert E Kaufman, MD 收起 <<
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