(S)-Oxiracetam
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货号：A982800
(S)-Oxiracetam 是一种靶向凋亡的抑制剂，在中风模型中通过激活 α7 nAChR-PI3K/Akt/GSK3β 通路阻止神经元凋亡，可减少脑梗面积并改善中风后神经功能障碍。
(S)-Oxiracetam 化学结构
(S)-Oxiracetam 3D分子结构
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(S)-Oxiracetam 纯度/质量文件 产品仅供科研
货号：A982800
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(S)-Oxiracetam 质控信息
(S)-Oxiracetam 生物活性
描述
Oxiracetam is a cyclic derivative of γ-aminobutyric acid (GABA) which has been commonly used as nootropic drug to treat cognitive impairments[3] [4] [5] [6] [7]
(S)-Oxiracetam 参考文献
[1] Yao XL, Yao ZH, et al. Oxiracetam can improve cognitive impairment after chronic cerebral hypoperfusion in rats. Psychiatry Res. 2016 Dec 30;246:284-292.
[2] Li JW, Yang DJ, et al. [Protective effect of oxiracetam on traumatic brain injury in rats] . Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2013 Jul;29(4):298-300.
[3] Hu S, Shi J, Xiong W, Li W, Fang L, Feng H. Oxiracetam or fastigial nucleus stimulation reduces cognitive injury at high altitude. Brain Behav. 2017 Aug 23;7(10):e00762
[4] Zhang H, Jia L, Jia J. Oxiracetam Offers Neuroprotection by Reducing Amyloid β-Induced Microglial Activation and Inflammation in Alzheimer's Disease. Front Neurol. 2020 Jul 17;11:623
[5] Xu J, Qi Q, Lv P, Dong Y, Jiang X, Liu Z. Oxiracetam ameliorates cognitive deficits in vascular dementia rats by regulating the expression of neuronal apoptosis/autophagy-related genes associated with the activation of the Akt/mTOR signaling pathway. Braz J Med Biol Res. 2019 Nov 7;52(11):e8371
[6] Hokonohara T, Sako K, Shinoda Y, Tomabechi M, Yonemasu Y. The effects of oxiracetam (CT-848) on local cerebral glucose utilization after focal cerebral ischemia in rats. Jpn J Pharmacol. 1992 Feb;58(2):127-35
[7] Sun Y, Xu B, Zhang Q. Nerve growth factor in combination with Oxiracetam in the treatment of Hypertensive Cerebral Hemorrhage. Pak J Med Sci. 2018 Jan-Feb;34(1):73-77
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(S)-Oxiracetam 实验方案
计算器
摩尔计算器
总药量计算器
工作液计算器
存储液制备
1mg
5mg
10mg
1 mM
5 mM
10 mM
6.32mL
1.26mL
0.63mL
31.61mL
6.32mL
3.16mL
63.23mL
12.65mL
6.32mL
(S)-Oxiracetam 技术信息
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