Phellodendrine chloride是从黄柏树皮中分离纯化的天然产物，具有抗肾炎作用，可能通过抑制小管中的巨噬细胞和细胞毒性 T 淋巴细胞的增殖或迁移起作用。还通过调节 AKT/NF-κB 通路抑制 AAPH 引起的氧化应激。

Jatrorrhizine是从一些植物种类（如Enantia chlorantha）中提取的原小檗碱生物碱，能够非竞争性抑制MAO-A和MAO-B，IC50分别为4μM和62μM，同时具有抗炎、抗微生物和抗真菌活性。

Obacunone是一种从黄柏树皮中提取的天然三萜类化合物，具有抗肿瘤活性，并能够通过抑制芳香化酶和炎症通路来预防雌激素依赖型乳腺癌，IC50为28.04 μM。

D-Tetrahydropalmatine, a natural product isolated and purified from the barks of Phellodendron chinense Schneid, is an organic cation transporter 1 (OCT1) inhibitor, and obviously inhibits the uptake of MCT in MDCK-hOCT1 cells and isolated rat primary hepatocytes, and attenuates the viability reduction and LDH release of the primary cultured rat hepatocytes caused by MCT.

Sinapaldehyde glucoside is a natural product isolated and purified from the barks of Phellodendron amurense.

Phellamurin, a natural product isolated and purified from the barks of Phellodendron chinense Schneid., inhibits intestinal P-glycoprotein in a dose-dependent manner.