YM-244769 2HCl是一种有效、选择性的、具有口服活性的 Na⁺/Ca²⁺ 交换体 (NCX) 抑制剂，优先抑制 NCX3，抑制 NCX 单向向外电流 (Ca²⁺ 进入模式)，IC50 分别为 18 nM 和 50 nM，可有效预防缺氧/复氧诱导的 SH-SY5Y 神经元细胞损伤，还能增加小鼠的尿量和尿液中电解质的排泄。

YM-244769是一种有效的、选择性的、具有口服活性的 Na⁺/Ca²⁺ 交换体（NCX）抑制剂，优先抑制 NCX3，并对 NCX 单向向外电流（Ca²⁺ 进入模式）的 IC50 值为 18 nM 和 50 nM。它可有效预防缺氧/复氧诱导的 SH-SY5Y 神经元细胞损伤，还能增加小鼠的尿量和尿液中电解质的排泄。

Benzamil hydrochloride is a specific blocker of sodium channel (ENaC).

CGP37157 is a potent, selective inhibitor of Na+/Ca2+ exchanger, inhibiting the Na+-induced Ca2+-release from guinea-pig heart mitochondria, with an IC50 of 0.8 μM.

SEA0400是一种新型选择性的Na+-Ca2+交换器（NCX）抑制剂，抑制培养的神经元、星形胶质细胞和小胶质细胞中的Na+依赖性Ca2+摄取，IC50范围为5到33 nM。

KYP-2047是一种有效的、可穿透血脑屏障的脯氨酸寡肽酶 (POP) 抑制剂，其 Ki 值为 0.023 nM。KYP-2047 通过调节血管生成和细胞凋亡，显著减少胶质母细胞瘤的增殖，具有研究脑肿瘤的潜力。

SN6 is a selective inhibitor used to reverse mode of the Na+/Ca2+ exchanger with IC50 value of 2.9, 16 and 8.6 μM for inhibition of intracellular Na+-dependent Ca2+ uptake by cells expressing NCX1, NCX2 and NCX3 respectively.

KB-R7943 Mesylate is a potent and selective inhibitor used to reverse mode of the Na+/Ca2+ exchanger with IC50 value of 0.7 μM. It also inhibits the mitochondrial Ca2+ uniporter with IC50 value of 5.5 μM.

Caldaret is an intracellular Ca2+ handling modulator that acts through reverse mode Na+/Ca2+ exchanger inhibition.

PPADS tetrasodiuma is a non-selective antagonist of P2X receptor. It blocks recombinant P2X1, -2, -3, -5 with IC50s ranging from 1 to 2.6 μM.