Tau-aggregation and neuroinflammation-IN-1是一种有效的 Tau 蛋白聚集体和神经炎症抑制剂，对 AcPHF6 和全长 tau 蛋白聚集体有显著的抑制作用，对 LSP 刺激的 BV2 细胞显示出低细胞毒性，并减少 NO 的释放，能够逆转冈田酸诱导的大鼠记忆障碍。

D-64131 is a novel tubulin polymerization inhibitor working by competitively binding with colchicine to αβ-tubulin.

BNC105 is a tubulin polymerization inhibitor with potent antiproliferative and tumor vascular disrupting properties.

Myoseverin is a microtuble-binding molecule and reversible inhibitor of tubulin polymerization. It binds to tublin leading to multinucleated myotubes fission.

T-1101 tosylate is a Hec1/Nek2 (Highly expressed in cancer 1 / NIMA-related kinase 2) inhibitor with antitumor activity. T-1101 tosylate is inactive toward normal cells, kinases and hERG.

(+)-Griseofulvin is a naturally occuring centrosomal clustering inhibitor and induces keratin cytoskeleton alterations. It is also an antifungal drug.

SSE15206 is a microtubule depolymerizing agent which inhibits microtubule polymerization both in biochemical and cellular assays by binding to colchicine site in tubulin. It causes aberrant mitosis resulting in G2/M arrest due to incomplete spindle formation.

Cephalomannine, a natural product isolated and purified from the barks of Cephalotaxus sinensis (Rehd. et Wils.) Li, is a taxol derivative with antitumor, antiproliferative properties.

Vinorelbine is an anti-mitotic agent which inhibits the proliferation of Hela cells with IC50 of 1.25 nM.

(S)-Dolaphenine HCl是 Dolastatin 10 的成分，Dolastatin 10 是一种抑制微管蛋白聚合的抗肿瘤剂。

Fenbendazole-d3是氘标记的 Fenbendazole，可作为 HIF-1α 激动剂，激活与 HIF-1α 相关的 GLUT1 通路。Fenbendazole 是一种具有广泛抗寄生虫活性的口服活性苯并咪唑驱虫剂，同时也是一种微管去稳定剂。Fenbendazole 能导致细胞周期停滞和有丝分裂细胞死亡，并在野生型 p53 异种移植小鼠中展现抗肿瘤活性。

TTBK1-IN-2是一种有效的 Tau-Tubulin 激酶 (TTBK1) 抑制剂，IC₅₀ 值分别为 0.24 和 4.22 µM。它具有良好的脑穿透性，能降低细胞和小鼠模型中 TDP-43 的磷酸化水平，适用于神经退行性疾病如 ALS 和阿尔茨海默症的研究。

Sabizabulin是一种高效、口服可利用的α/β微管蛋白(tubulin)抑制剂，对黑色素瘤和前列腺癌细胞具有强效抗增殖活性（IC₅₀=5.2 nM）。该化合物通过靶向HPV E6和E7抑制肿瘤生长和转移，适用于前列腺癌的研究。

VcMMAE(MC-Val-Cit-PAB-MMAE) (GMP) 按照 GMP 指南生产，用作 ADCs 的药物-连接子偶联物。

Ixabepilone is a microtubule inhibitor working by binding to tubulin and promoting tubulin polymerization and microtubule stabilization.

Indibulin is a microtubule destabilizer that blocks tubulin polymerization with IC50 of 0.3 μM.

Colcemid是一种有效的微管蛋白 (tubulin) 抑制剂，用于研究有丝分裂过程和细胞周期调控，其在抗癌研究中发挥重要作用。

Fosbretabulin disodium is the water-soluble prodrug of Combretastatin A4 (CA4), which is a microtubule-targeting agent that binds β-tubulin with Kd of 0.4 μM in a cell-free assay. Fosbretabulin disodium inhibits the polymerization of tubulin with IC50 of 2.4 μM, and also disrupts tumor vasculature.

BTB1 an ATP-competitive and selective inhibitor of the mitotic motor protein Kif18A with IC50 value of 1.7 μM.

Nek2/Hec1-IN-2 是 Nek2/Hec1 的抑制剂，能够抑制癌细胞增殖，IC50 值大于 25 μM。