Laduviglusib (CHIR-99021)是一种有效、选择性且具有口服活性的 GSK-3α/β 抑制剂，可用作细胞疗法中的辅助试剂。

SB-216763是一种高效、选择性和ATP竞争性的GSK-3抑制剂，对GSK-3α和GSK-3β的IC50均为34.3 nM。

CHIR-98014 (CT98014) is highly selective aminopyrimidine-derivatived inhibitor of GSK-3 with IC50 of 650nM and 580nM for GSK-3 and GSK-3(measured by kinase assays), respectively, and exhibits >1000-fold selectivity for GSK-3 over closely related kinases, such as cdc2.

TWS119 is inhibitor of glycogen synthase kinase-3β with IC50 of 30 nM.

Tideglusib is an irreversible GSK-3 inhibitor with IC50 of 5 nM and 60 nM for GSK-3βWT (1 h preincubation) and GSK-3βC199A (1 h preincubation), respectively.

SB-415286 is an ATP-competitive inhibitor of GSK3α/GSK3β with IC50 of 78 nM and Ki of 31 nM.

AZD1080 is a selective, orally active, brain permeable GSK3 inhibitor of GSK3α and GSK3β with Ki of 6.9 nM and 31 nM, respectively, shows > 14-fold selectivity against CDK2, CDK5, CDK1 and Erk2.

AR-A014418 is a selective inhibitor of GSK3β with IC50 of 104 ± 27 nM.

TDZD-8, the derivative of thiadiazolidinone, is a selective inhibitor of GSK-3. It inhibits GSK-3β with IC50 of 2 μM.

LY2090314是一种高效的糖原合成酶激酶-3（GSK-3）抑制剂，对GSK-3α和GSK-3β的IC50值分别为1.5 nM和0.9 nM。

IM-12 is a GSK-3β inhibitor with IC50 of 53 nM.

1-Azakenpaullone（1-Akp）是一种高度选择性的、ATP竞争性的糖原合成酶激酶-3β（GSK-3β）抑制剂，其IC50值为18 nM。

Indirubin is a purple 3,2- bisindole and a stable isomer of indigo isolated from Indigo naturalis (Apiaceae) with anti-inflammatory and anticancer activities.

BIO-acetoxime is an inhibitor of GSK3α and GSK3β with IC50 of 10 nM.