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AH 7614 is a selective free fatty acid receptor 4 (FFA4/GPR120) antagonist with pIC50 of 7.1 for human FFA4.
DC260126 is antagoniat of free fatty acid receptor 1 (FFA1/GPR40) and inhibits FFA-induced the increase of intracellular Ca2+ level.
TAK-875 is a selective GPR40 agonist with EC50 of 14 nM in human GPR40 expressing CHO cell line, 400-fold more potent than oleic acid.
AM-1638 is a potent and orally bioavailable GPR40/FFA1 full agonist with an EC50 of 0.16 μM.
GW1100 is a selective antagonist of GPR40-mediated Ca2+ elevations in HEK293 cells stimulated by GW 9508 or linoleic acid with a pIC50 value equal to 5.99.
PBI-4050 acts as an agonist for GPR40 and as an antagonist or inverse agonist for GPR84.
Tags: GPR40 | G蛋白偶联受体/G蛋白 | GPCR/G Protein | GPR40 相关产品
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