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货号 产品名 纯度
A1176693 现货 Synta66

Synta66是一种钙离子通道 Orai (CRAC 的核心) 的有效抑制剂,适用于与钙信号传导相关的神经和免疫系统疾病的研究。

99%
A542408 现货 CRAC intermediate 1

CRAC intermediate 1是一种药物中间体,常用于 CRAC 离子通道化合物的合成,广泛用于离子通道功能的研究。

99%+
A605542 现货 Zegocractin

CM4620 is a CRAC channel inhibitor to treat acute pancreatitis.

99%+
A724629 现货 GSK-7975A

GSK-7975A is a potent and orally available CRAC channel inhibitor.

98%
A255311 现货 Tanshinone IIA sulfonate sodium/丹参酮IIA-磺酸钠

Tanshinone IIA sulfonate sodium is a water-soluble derivative of tanshinone IIA, which acts as an inhibitor of store-operated Ca2+entry (SOCE), and is used to treat cardiovascular disorders.

98%
A172938 现货 YM-58483

YM-58483 是一种选择性的钙释放活化钙通道(CRAC)抑制剂,对 Orai1 具有高亲和力,IC50 值为 10 nM。YM-58483 具有免疫调节和抗炎作用,可用于自身免疫性疾病和炎症相关疾病的研究。

99%+
A1210845 现货 NDMC101

NDMC101 is a potent osteoclastogenesis inhibitor and inhibits osteoclast differentiation via down-regulation of NFATc1-modulated gene express. NDMC101 is similar to the DPP4 substrate and is a significant inhibitor of early T-cell activation via DPP4 inhibition. NDMC101can be used for study of bone disorders, such as rheumatoid arthritis, and synovial inflammation et al .

99%+
A1601798 piCRAC-1

98%
A1145748 MRS1845

MRS 1845 is a potent SOCE inhibitor with can block capacitative Ca2+ entry with IC50 value of 1.7μM in HL-60 cells.

98%
A1176953 SOCE inhibitor 1

A1597294 5J-4

95%
A1806355 GSK-5503A

98%
A228881 GSK-5498A

GSK5498A is a selective small molecule blocker of CRAC channel(IC50=1 uM) and inhibit mediator release from mast cells, and pro-inflammatory cytokine release from T-cells in a variety of species.

98+%
A1365266 RO2959 monohydrochloride

98%
A1359439 RO2959 hydrochloride

97%
A2792293 Zegocractin

99%
A2795191 GSK-7975A

99%
A2791659 YM-58483

99%
A2791614 NDMC101

99%
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