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AN2是一种 mHTT-LC3 连接化合物,能够特异性与突变型亨廷顿蛋白 (mHTT) 和 LC3B 结合,降低亨廷顿病 (HD) 小鼠神经元中的 mHTT 水平,适用于亨廷顿病的研究。
Bergaptol 是一种抑制 CYP3A4 酶去甲基化活性的抑制剂,IC50 为 24.92 μM。最近的研究表明其具有抗增殖和抗癌特性。
Byakangelicin, a main furanocoumarin constituent isolated and characterized as an aldose reductase inhibitor from the roots of Angelica dahurica, is an aldose reductase inhibitor and induces cytochrome P450 3A4 expression via transactivation of pregnane X receptors in human hepatocytes.
Nodakenin is a natural product isolated and purified from the root of Angelica biserrata (Shan et Yuan) Yuan et Shan. with anti-aggregatory, antibacterial, anti-allergic, anti- inflammator, and memory-enhancing effects.
5,7-Dihydroxycoumarin是从 Macaranga triloba 花序中分离得到的一种香豆素,展示了显著的抗菌活性,适用于微生物学和天然产物药物开发的研究。
6-Hydroxycoumarin是香豆素的衍生物,具有抗炎、抗氧化和支气管扩张等药理活性。它在药物研发和治疗研究中具有应用价值。
4-Methoxycoumarine is an intermediate.
Knidilin is one of the major bioactive constituents of radix angelicae dahuricae, it can be used to treat headache, toothache, abscess, furunculosis and acne.
7-Amino-4-methyl-3-coumarinylacetic acid (AMCA) is fluorescent protein labeling agent.1 It contains an N-hydroxysuccinimide ester that reacts with lysine residues to form photostable amide links. Upon activation with UV light, AMCA displays emission maxima of 400-460 nm. It has commonly been used in multiplex immunophenotyping applications.
Glycycoumarin, a natural product isolated and purified from Glycyrrhizae Radix, inhibits hepatocyte lipoapoptosis through activation of autophagy and inhibition of ER stress/GSK-3-mediated mitochondrial pathway.
Tags: 香豆素 | Coumarins | 结构分类 | By Structure | 香豆素 相关产品
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