CM037是一种选择性 ALDH1A1 (乙醛脱氢酶 1A1) 的抑制剂，IC50 为 4.6 µM。

CVT 10216 is a potent and selective aldehyde dehydrogenase-2 (ALDH2) inhibitor with IC50s of 29 and 1300 nM for ALDH2 and ALDH1, respectively.

RV01是白藜芦醇类似物，能够抑制 DNA 损伤，降低乙醇诱导的乙醛脱氢酶 (ALDH2) 的 mRNA 表达，并具有清除羟自由基的活性，还能降低 iNOS 的表达，具备抗神经炎症作用。

NCT-505是一种选择性乙醛脱氢酶 (ALDH1A1) 抑制剂，IC₅₀值为7 nM，对其他ALDH同工酶的抑制作用较弱。NCT-505 可用于研究ALDH1A1介导的癌症干细胞特性，适合用于癌症及干细胞治疗的研究。

NCT-501 is a potent and selective theophylline-based inhibitor of aldehyde dehydrogenase 1A1 (ALDH1A1), inhibits hALDH1A1 with IC50 of 40 nM, typically shows better selectivity over other ALDH isozymes and other dehydrogenases (hALDH1B1, hALDH3A1, and hALDH2, IC50 > 57 μM).

Alda-1是一种高效选择性的ALDH2激动剂，能激活野生型ALDH2并恢复ALDH2*2的接近野生型活性。

WIN 18446 is an inhibitor of aldehyde dehydrogenase 1a2 (ALDH1a2) with IC50 of 0.3 μM.

Prunetin是一种 O-甲基化异黄酮，具有抗炎活性，同时能够抑制人醛脱氢酶，在抗炎及代谢相关疾病研究中具有潜力。

Daidzin can inhibit mitochondrial aldehyde dehydrogenase2 with IC50 of 80 nM and ALDH-I selectively (Ki=20 nM). Daidzin is purified from the root of Pueraria lobata with effective anti-atherosclerotic activities.

Disulfiram is a specific inhibitor of aldehyde-dehydrogenase (ALDH1), used for the treatment of chronic alcoholism by producing an acute sensitivity to alcohol. Disulfiram acts as an allosteric inhibitor of MERS-CoV PLpro but as a competitive (or mixed) inhibitor of SARS-CoV PLpro. It also inhibits pyroptosis by blocking gasdermin D pore formation.

4-Diethylaminobenzaldehyde是一种可逆的醛脱氢酶 (ALDH) 抑制剂，对 ALDH1 的 Ki 值为 4 nM，并且表现出较强的抗雄激素活性，IC50 为 1.71 μM。

Taraxerone, a natural product isolated and purified from the herb of Taraxacum mongolicum Hand. Mazz. with allelopathic and antifungal activities, prevents catalase, superoxide dismutase, and reduces glutathione concentrations from the decrease induced by ethanol administration with the concentration dependent manner.

Prunetin can inhibit the aldehyde dehydrogenases in liver. It is a flavonoid compound isolated from the herbs of millettia dielsiana.

3,4-Dihydroxyphenylacetic Acid is a metabolite of dopamine, it can modulate the aldehyde dehydrogenase (ALDH) activity and protects the cells from the acetaldehyde-induced cytotoxicity in vitro.