Verinurad is an inhibitor of urate transporter with EC50 of 0.05 μM.

Lesinurad is a URAT1 inhibitor with IC50 of 3.5 µM. It acts as a transporter that regulates uric acid excretion in kidney.

Zerumbone, a monocyclic sesquiterpene compound isolated from the rhizomes of Zingiber zerumbet Smith, potently inhibits the activation of Epstein-Barr virus with an IC50 of 0.14 mM. Zerumbone has anti-cancer, antioxidant, anti-inflammatory and anti-proliferative activity[1][2].

Metronidazole is an inhibitor of OAT3 and can inhibit the transport activity of OAT3 with IC50 and Ki of 6.51 ± 0.99 μM, 6.48 μM, respectively. It is also an antibacterial agent for anaerobic bacteria and protozoa.

Lesinurad sodium is an inhibitor of URAT1 and OAT and it is also a substrate for the kidney transporters OAT1 and OAT3 with Km values of 0.85 and 2 µM, respectively.