Geissoschizine methyl ether is a potent serotonin A receptor agonist.

Rhyncholphylline, an alkaloid isolated and purified from the herbs of Uncaria rhynchophylla., can protect against ischemic damage and glutamate-induced neuronal death, and also inhibit MA impairment in cultured neurons in vitro. Ca2+ channel blocker.

Linarin, a natural product isolated and purified from the herb of Uncaria sinensis (Oliv.) Havil., prevents a beta-induced neurotoxicity through the activation of PI3K/Akt, which subsequently inhibits GSK-3b and up-regulates Bcl-2.

Isocorynoxeine, a major alkaloid found in Uncaria rhynchophylla, exhibits wide beneficial effects on the cardiovascular and cardiocerebral vascular systems.

Corynoxine is an enantiomer of Corynoxine B and induces autophagy in different neuronal cell lines, including N2a and SHSY-5Y cells.

Corynoxeine is a potent ERK1/2 inhibitor of key PDGF-BB-induced VSMC proliferation, and is a useful and prospective compound in the prevention and treatment for vascular diseases.

Hirsuteine, isolated from uncaria rhynchophylla, has potent neuroprotective effects against glutamate-induced HT22 cell death.

Hirsutine, an indole alkaloid isolated and purified from the herbs of Uncaria rhynchophylla, which can inhibits Late step in dengue virus lifecycle.

1,2-O-Isopropylidene-beta-D-fructopyranose is a natural product isolated and purified from the herbs of Uncaria sessilifructus.

Corynoxine B is an oxindole alkaloid isolated from Uncaria rhynchophylla (Miq.) Jacks (Gouteng in Chinese) and a Beclin-1-dependent autophagy inducer.