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Geissoschizine methyl ether是一种强效的5-HTA受体激动剂。
Rhyncholphylline是从钩藤(Uncaria rhynchophylla)中分离和纯化的生物碱,具有保护作用,可防止缺血性损伤和谷氨酸诱导的神经元死亡,并抑制培养神经元中的 MA 损伤作用,是一种钙通道阻滞剂。
Buddleoside是从 Uncaria sinensis(钩藤)草本植物中分离和纯化的天然产物,能够通过激活 PI3K/Akt 通路防止 β-淀粉样蛋白诱导的神经毒性,进而抑制 GSK-3b 并上调 Bcl-2。
Isocorynoxeine是从钩藤(Uncaria rhynchophylla)中提取的主要生物碱,对 5-HT2A 受体介导的电流反应具有剂量依赖性抑制作用,IC50 为 72.4 μM。它对心血管和脑血管系统具有多种有益作用,可用于相关疾病研究。
Corynoxine is an enantiomer of Corynoxine B and induces autophagy in different neuronal cell lines, including N2a and SHSY-5Y cells.
Corynoxeine is a potent ERK1/2 inhibitor of key PDGF-BB-induced VSMC proliferation, and is a useful and prospective compound in the prevention and treatment for vascular diseases.
Hirsuteine, isolated from uncaria rhynchophylla, has potent neuroprotective effects against glutamate-induced HT22 cell death.
Hirsutine, an indole alkaloid isolated and purified from the herbs of Uncaria rhynchophylla, which can inhibits Late step in dengue virus lifecycle.
1,2-O-Isopropylidene-beta-D-fructopyranose is a natural product isolated and purified from the herbs of Uncaria sessilifructus.
Corynoxine B is an oxindole alkaloid isolated from Uncaria rhynchophylla (Miq.) Jacks (Gouteng in Chinese) and a Beclin-1-dependent autophagy inducer.
Tags: 钩藤属 | Uncaria | 茜草科 | Rubiaceae | 钩藤属 相关产品
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