Harpagoside is a naturally occurring iridoid glycoside with anti-inflammatory effect.

8-O-Acetylharpagide, a natural product isolated and purified from the roots of Scrophularia ningpoensis Hemsl. with anti-inflammatory, antibacterial, and antiviral activities, has a biological activity on isolated smooth muscle preparations from guinea pig.

Angoroside C, a natural product isolated and purified from the roots of Scrophularia ningpoensis Hemsl., may participate in the anti-inflammatory effect of Scrophularia scorodonia.