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Xanthine oxidoreductase-IN-4 {[allProObj[0].p_purity_real_show]}

货号:A1810628

Xanthine oxidoreductase-IN-4 是一种口服活性黄嘌呤氧化还原酶 (XOR) 抑制剂,对 XORIC50 为 29.3 nM,适用于高尿酸血症研究。

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Xanthine oxidoreductase-IN-4 化学结构 CAS号:1026587-58-5
Xanthine oxidoreductase-IN-4 化学结构
CAS号:1026587-58-5
Xanthine oxidoreductase-IN-4 3D分子结构
CAS号:1026587-58-5
Xanthine oxidoreductase-IN-4 化学结构 CAS号:1026587-58-5
Xanthine oxidoreductase-IN-4 3D分子结构 CAS号:1026587-58-5
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Xanthine oxidoreductase-IN-4 纯度/质量文件 产品仅供科研

货号:A1810628 标准纯度: {[allProObj[0].p_purity_real_show]}
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Xanthine oxidoreductase-IN-4 生物活性

描述 Similarly, Xanthine oxidoreductase-IN-4 serves as an orally active inhibitor of xanthine oxidoreductase (XOR), exhibiting inhibitory potency against XOR with an IC50 value of 29.3 nM. Xanthine oxidoreductase-IN-4 is suitable for the study of hyperuricemia [1].
体内研究

Furthermore, administration of Xanthine oxidoreductase-IN-4 orally at a dose of 5 mg/kg demonstrates a notable hypouricemic effect in a potassium oxazinate/hypoxanthine-induced model of acute hyperuricemia [1].

体外研究

Xanthine oxidoreductase-IN-4 displays inhibitory activity against XOR, with an IC50 value of 29.3 nM [1].

Xanthine oxidoreductase-IN-4 参考文献

[1]Wen Peng, et al. Design, synthesis, and evaluation of tricyclic compounds containing phenyl-tetrazole as XOR inhibitors. Eur J Med Chem. 2022 Nov 28;246:114947.

Xanthine oxidoreductase-IN-4 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.23mL

0.65mL

0.32mL

16.16mL

3.23mL

1.62mL

32.33mL

6.47mL

3.23mL

Xanthine oxidoreductase-IN-4 技术信息

CAS号1026587-58-5
分子式C16H15N5O2
分子量 309.323
别名
运输蓝冰
存储条件

液体 -20°C:3-6个月-80°C:12个月

粉末 Inert atmosphere,2-8°C

溶解度
动物实验配方
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