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Xanthine oxidoreductase-IN-4

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Chemical Structure| 1026587-58-5 同义名 : -
CAS号 : 1026587-58-5
货号 : A1810628
分子式 : C16H15N5O2
纯度 : 99%+
分子量 : 309.323
MDL号 : -
存储条件：

粉末 Inert atmosphere,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 Similarly, Xanthine oxidoreductase-IN-4 serves as an orally active inhibitor of xanthine oxidoreductase (XOR), exhibiting inhibitory potency against XOR with an IC50 value of 29.3 nM. Xanthine oxidoreductase-IN-4 is suitable for the study of hyperuricemia [1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.23mL

0.65mL

0.32mL

16.16mL

3.23mL

1.62mL

32.33mL

6.47mL

3.23mL
参考文献

[1]Wen Peng, et al. Design, synthesis, and evaluation of tricyclic compounds containing phenyl-tetrazole as XOR inhibitors. Eur J Med Chem. 2022 Nov 28;246:114947.