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戊沙溴铵 /Valethamate bromide {[allProObj[0].p_purity_real_show]}

货号:A439776

Valethamate bromide is generally used as an anticholinergic agent.

Valethamate bromide 化学结构 CAS号:90-22-2
Valethamate bromide 化学结构
CAS号:90-22-2
Valethamate bromide 3D分子结构
CAS号:90-22-2
Valethamate bromide 化学结构 CAS号:90-22-2
Valethamate bromide 3D分子结构 CAS号:90-22-2
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Valethamate bromide 纯度/质量文件 产品仅供科研

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Valethamate bromide 生物活性

描述 Valethamate bromide is an ester and is a potent rapidly acting anticholinergic spasmolytic and musculotropic agent which accelerates labor by improving cervical dilatio[3]. Side effects such as tachycardia, flushing of the face and dryness of mouth were noted with valethamate bromide administration. Valethamate bromide did not significantly shortened the duration of active labour in nulliparous women with a singleton pregnancy at term[4]. Both Drotaverine and Valethamate appear to significantly help cervical dilatation and augment first stage of labour[5].

Valethamate bromide 参考文献

[1]Kostu B, Kiran G, et al. A randomised controlled study comparing valethamate bromide and placebo in shortening the duration of active labour. J Obstet Gynaecol. 2016;36(2):196-9.

[2]Stanton C, Nand DN, et al. Accessibility and potency of uterotonic drugs purchased by simulated clients in four districts in India. BMC Pregnancy Childbirth. 2014 Nov 13;14:386.

[3]Sharma JB, Pundir P, Kumar A, Murthy NS. Drotaverine hydrochloride vs. valethamate bromide in acceleration of labor. Int J Gynaecol Obstet. 2001 Sep;74(3):255-60

[4]Köstü B, Kiran G, Ercan Ö, Bakacak M, Bostanci MS, Arikan D, Özdemir Ö. A randomised controlled study comparing valethamate bromide and placebo in shortening the duration of active labour. J Obstet Gynaecol. 2016;36(2):196-9

[5]Madhu C, Mahavarkar S, Bhave S. A randomised controlled study comparing Drotaverine hydrochloride and Valethamate bromide in the augmentation of labour. Arch Gynecol Obstet. 2010 Jul;282(1):11-5

Valethamate bromide 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.59mL

0.52mL

0.26mL

12.94mL

2.59mL

1.29mL

25.88mL

5.18mL

2.59mL

Valethamate bromide 技术信息

CAS号90-22-2
分子式C19H32BrNO2
分子量 386.367
别名
运输蓝冰
存储条件

液体 -20°C:3-6个月-80°C:12个月

粉末 Inert atmosphere,Room Temperature

溶解度

DMSO: 105 mg/mL(271.76 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

H2O: 50 mg/mL(129.41 mM),配合低频超声助溶

动物实验配方
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