货号:A151541 同义名: Temocapril (hydrochloride);CS-622 HCl
Temocapril HCl is a long-acting and prodrug-type ACE inhibitor,not approved for use in US, but approved in Japan and South Korea.
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描述 | Temocapril hydrochloride is a novel prodrug-type angiotensin-I converting enzyme (ACE) inhibitor, lowering of the dose of temocapril might be recommended only in patients with severe renal insufficiency[3]. Temocapril hydrochloride decreases tumor tBF (tissue blood flow) markedly in LY80 tumor, a subline of Yoshida sarcoma in the rat, without affecting the blood flow in liver, kidney, bone marrow, and brain[4]. |
计算器 | ||||
存储液制备 | 1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
1.95mL 0.39mL 0.19mL |
9.75mL 1.95mL 0.97mL |
19.49mL 3.90mL 1.95mL |
CAS号 | 110221-44-8 |
分子式 | C23H29ClN2O5S2 |
分子量 | 513.07 |
别名 | Temocapril (hydrochloride);CS-622 HCl;CS 622;Temocapril hydrochloride |
运输 | 蓝冰 |
存储条件 |
液体 -20°C:3-6个月-80°C:12个月 粉末 Inert atmosphere,Store in freezer, under -20°C |
溶解度 |
DMSO: 60 mg/mL(116.94 mM),配合低频超声,并水浴加热至45℃助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO H2O: 2 mg/mL(3.9 mM),配合低频超声,并水浴加热至45℃助溶 |
动物实验配方 |
IP 2% DMSO+2% Tween80+40% PEG300+water 6 mg/mL clear PO 0.5% CMC-Na 20 mg/mL suspension |