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三肉豆蔻酸甘油酯 /TRIMYRISTIN {[allProObj[0].p_purity_real_show]}

货号:A244569 同义名: 甘油三肉豆蔻酸酯 / 1,2,3-Trimyristoyl Glycerol;Tritetradecanoin

Trimyristin is used as a lipophilic and nanoparticles carriers loaded with proteins. It is triacylglycerol of myristic acid found in nutmeg.

TRIMYRISTIN 化学结构 CAS号:555-45-3
TRIMYRISTIN 化学结构
CAS号:555-45-3
TRIMYRISTIN 3D分子结构
CAS号:555-45-3
TRIMYRISTIN 化学结构 CAS号:555-45-3
TRIMYRISTIN 3D分子结构 CAS号:555-45-3
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TRIMYRISTIN 纯度/质量文件 产品仅供科研

货号:A244569 标准纯度: {[allProObj[0].p_purity_real_show]}
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TRIMYRISTIN 生物活性

描述 Trimyristin is used as a lipophilic and nanoparticles carriers loaded with proteins. It is triacylglycerol of myristic acid found in nutmeg. Trimyristin, an active molluscicidal component of Myristica fragrans Houtt, significantly inhibits acetylcholinesterase (AChE), acid and alkaline phosphatase (ACP/ALP) activities in the nervous tissue of Lymnaea acuminata. IC50s of Trimyristin against AChE, ACP, and ALP are 0.11, 0.16 and 0.18 mM, respectively[1]. Trimyristin caused significant rises in low-density lipoprotein (LDL) cholesterol which were accompanied by significant reductions in hepatic LDL receptor mRNA levels[2]. In hamsters fed high fat diets enriched in trimyristin, tripalmitin or tristearin, increased dietary cholesterol content was associated with increased plasma concentrations of very low density lipoprotein (VLDL) cholesterol and triacylglycerol[3].

TRIMYRISTIN 参考文献

[1]Jaiswal P, Kumar P, Singh VK, Singh DK. Enzyme Inhibition by Molluscicidal Components of Myristica fragrans Houtt. in the Nervous Tissue of Snail Lymnaea acuminata. Enzyme Res. 2010;2010:478746

[2]Bennett AJ, Billett MA, Salter AM, Mangiapane EH, Bruce JS, Anderton KL, Marenah CB, Lawson N, White DA. Modulation of hepatic apolipoprotein B, 3-hydroxy-3-methylglutaryl-CoA reductase and low-density lipoprotein receptor mRNA and plasma lipoprotein concentrations by defined dietary fats. Comparison of trimyristin, tripalmitin, tristearin and triolein. Biochem J. 1995 Oct 1;311 ( Pt 1)(Pt 1):167-73

[3]Bennett AJ, Bruce JS, Salter AM, White DA, Billett MA. Hepatic microsomal triglyceride transfer protein messenger RNA concentrations are increased by dietary cholesterol in hamsters. FEBS Lett. 1996 Oct 7;394(3):247-50

TRIMYRISTIN 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.38mL

0.28mL

0.14mL

6.91mL

1.38mL

0.69mL

13.83mL

2.77mL

1.38mL

TRIMYRISTIN 技术信息

CAS号555-45-3
分子式C45H86O6
分子量 723.161
别名 甘油三肉豆蔻酸酯 ;1,2,3-Trimyristoyl Glycerol;Tritetradecanoin;Tritetradecanoyl Glycerol;TG(14:0/14:0/14:0);NSC 4062;Myristic Acid Triglyceride;Glycerol Tritetradecanoate
运输蓝冰
存储条件

液体 -20°C:3-6个月-80°C:12个月

粉末 Keep in dark place,Sealed in dry,Store in freezer, under -20°C

溶解度
动物实验配方
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