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磺胺噻唑 /Sulfathiazole {[allProObj[0].p_purity_real_show]}

货号:A227334

Sulfathiazole是一种短效磺胺类抗生素,主要通过抑制二氢叶酸合成酶来阻止二氢叶酸合成,具有一定毒性。

Sulfathiazole 化学结构 CAS号:72-14-0
Sulfathiazole 化学结构
CAS号:72-14-0
Sulfathiazole 3D分子结构
CAS号:72-14-0
Sulfathiazole 化学结构 CAS号:72-14-0
Sulfathiazole 3D分子结构 CAS号:72-14-0
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Sulfathiazole 纯度/质量文件 产品仅供科研

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Sulfathiazole 生物活性

描述 Sulfathiazole, an organosulfur compound, is used as a short-acting sulfonamide antibiotic.Recovery from spiked manure slurry samples is 64% for Sulfathiazole at pH 9. Sulfathiazole has acidity constant of pKa of 7.1and retention times (tR) of 7.8. S/N values for Sulfathiazole are above 100 at the 1 mg/kg level[3]. Sulfathiazole sorption to inorganic sorbents exhibited pronounced pH dependence consistent with sorbate speciation and sorbent charge properties.Sulfathiazole cations were most important for sorption to clay minerals [4]. The sorption of STZ (Sulfathiazole) on GMC-treated(giant Miscanthus) soils is greatly enhanced, mainly through the greater micropore surfaces, the abundance of hydrophilic functional groups over time, and π+-π electron donor-acceptor interaction at low pH[5].

Sulfathiazole 参考文献

[1]Perez S, Eichhorn P, Aga DS. Evaluating the biodegradability of sulfamethazine, sulfamethoxazole, sulfathiazole, and trimethoprim at different stages of sewage treatment. Environ Toxicol Chem. 2005 Jun;24(6):1361-7.

[2]Haller MY, Muller SR, et al. Quantification of veterinary antibiotics (sulfonamides and trimethoprim) in animal manure by liquid chromatography-mass spectrometry. J Chromatogr A. 2002 Apr 5;952(1-2):111-20.

[3]Haller MY, Müller SR, McArdell CS, Alder AC, Suter MJ. Quantification of veterinary antibiotics (sulfonamides and trimethoprim) in animal manure by liquid chromatography-mass spectrometry. J Chromatogr A. 2002;952(1-2):111–120

[4]Kahle M, Stamm C. Time and pH-dependent sorption of the veterinary antimicrobial sulfathiazole to clay minerals and ferrihydrite. Chemosphere. 2007;68(7):1224–1231

[5]Kim H, Kim J, Kim M, Hyun S, Moon DH. Sorption of sulfathiazole in the soil treated with giant Miscanthus-derived biochar: effect of biochar pyrolysis temperature, soil pH, and aging period. Environ Sci Pollut Res Int. 2018;25(26):25681–25689

Sulfathiazole 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.92mL

0.78mL

0.39mL

19.58mL

3.92mL

1.96mL

39.17mL

7.83mL

3.92mL

Sulfathiazole 技术信息

CAS号72-14-0
分子式C9H9N3O2S2
分子量 255.317
别名
运输蓝冰
存储条件

In solvent -20°C:3-6个月-80°C:12个月

Pure form Keep in dark place,Inert atmosphere,Room temperature

溶解度

DMSO: 250 mg/mL(979.18 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方
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