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Sulfaguanidine
磺胺脒 /Sulfaguanidine
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货号：A293011
同义名：
磺胺胍
Sulfaguanidine is a DHFR inhibitor showing antibacterial effects against Gram-negative and Gram-postitive bacteria.
Sulfaguanidine 化学结构
Sulfaguanidine 3D分子结构
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Sulfaguanidine 纯度/质量文件 产品仅供科研
货号：A293011
标准纯度：
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Sulfaguanidine 质控信息
Sulfaguanidine 生物活性
描述
Sulfaguanidine (SG), belongs to the class of sulfonamide drug used as an effective antibiotic. Cocrystal SG-TBA showed better antibacterial activity and reduced hemolysis, thereby, reduced cytotoxicity than SG-PT (SG were synthesized with thiobarbutaric acid and 1,10-phenanthroline)[2] [3] [4]
Sulfaguanidine 参考文献
[1] Mizuno N, Nishikata M, et al. Gastrointestinal absorption of sulfaguanidine in neonatal and adult rats. J Pharmacobiodyn. 1986 Oct;9(10):787-92.
[2] Abidi SSA, Azim Y, Khan SN, Khan AU. Sulfaguanidine cocrystals: Synthesis, structural characterization and their antibacterial and hemolytic analysis. J Pharm Biomed Anal. 2018;149:351–357
[3] Mizuno N, Nishikata M, Morita E, Miyake K. Gastrointestinal absorption of sulfaguanidine in neonatal and adult rats. J Pharmacobiodyn. 1986;9(10):787–792
[4] Kastalli S, El Aidli S, Daghfous R, et al. Erythème pigmenté fixe à la sulfaguanidine [Fixed drug eruption induced by sulfaguanidine]. Ann Dermatol Venereol. 2004;131(4):382–384
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Sulfaguanidine 实验方案
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1mg
5mg
10mg
1 mM
5 mM
10 mM
4.67mL
0.93mL
0.47mL
23.34mL
4.67mL
2.33mL
46.68mL
9.34mL
4.67mL
Sulfaguanidine 技术信息
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