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磺胺嘧啶 /Sulfadiazine {[allProObj[0].p_purity_real_show]}

货号:A293414 同义名: NSC 35600

Sulfadiazine is a synthetic pyrimidinyl short-acting sulfonamide antibiotic used to treat urinary tract infections, ear infections, meningitis, malaria, toxoplasmosis, and others.

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There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.

Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Sulfadiazine 化学结构 CAS号:68-35-9
Sulfadiazine 化学结构
CAS号:68-35-9
Sulfadiazine 3D分子结构
CAS号:68-35-9
Sulfadiazine 化学结构 CAS号:68-35-9
Sulfadiazine 3D分子结构 CAS号:68-35-9
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Sulfadiazine 纯度/质量文件 产品仅供科研

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Sulfadiazine 生物活性

描述 Sulfadiazine is a bacteriostatic antibacterial agent that interferes with folic acid synthesis in susceptible bacteria. The combination of Trimethoprim and Sulfadiazine produces a synergistic effect against both Gram-positive and Gram-negative aerobic bacteria[3]. Sulfadiazine (SD) is a classic antibiotic for intracranial infection. It should be offered as an option for the patients with refractory intracranial infection, especially for patients with lower ability to pay[4]. Sulfadiazine is a sulfonamide antibiotic used for the treatment of toxoplasmosis. In 100 percent of the ulcers treated with silver sulfadiazine cream (15 patients) the bacterial counts were reduced to 10(5) or less per gram of tissue within the three-week test period, compared to 78.6 percent in those treated with saline (14 patients) and 63.6 percent in those treated with povidone-iodine solution (11 patients). Moreover, the ulcers treated with silver sulfadiazine cream responded more rapidly, with one-third showing bacterial levels of less than 10(5) within three days, and half within a week[5].

Sulfadiazine 参考文献

[1]Torre D, Casari S, et al. Randomized trial of trimethoprim-sulfamethoxazole versus pyrimethamine-sulfadiazine for therapy of toxoplasmic encephalitis in patients with AIDS. Italian Collaborative Study Group. Antimicrob Agents Chemother. 1998 Jun;42(6):1346-9.

[2]Kucan, J.O., et al. Comparison of silver sulfadiazine, povidone-iodine and physiologic saline in the treatment of chronic pressure ulcers. J Am Geriatr Soc, 1981. 29(5):232-5.

[3]Graves RA, Phan KV, Bostanian LA, Mandal TK, Pramar YV. Physicochemical Stability of an Oral Suspension of Trimethoprim 20 mg/mL in Combination with Sulfadiazine 200 mg/mL in PCCA Base SuspendIt. Int J Pharm Compd

[4]Zhang C, Hu L, Ding X, Lu Y, Hu G. The Role of Sulfadiazine for the Treatment of Refractory Intracranial Infection. Turk Neurosurg. 2015;25(6):895–899

[5]Kucan JO, Robson MC, Heggers JP, Ko F. Comparison of silver sulfadiazine, povidone-iodine and physiologic saline in the treatment of chronic pressure ulcers. J Am Geriatr Soc. 1981;29(5):232–235

Sulfadiazine 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

4.00mL

0.80mL

0.40mL

19.98mL

4.00mL

2.00mL

39.96mL

7.99mL

4.00mL

Sulfadiazine 技术信息

CAS号68-35-9
分子式C10H10N4O2S
分子量 250.28
别名 NSC 35600
运输蓝冰
存储条件

液体 -20°C:3-6个月-80°C:12个月

粉末 Keep in dark place,Sealed in dry,Room Temperature

溶解度

DMSO: 50 mg/mL(199.78 mM),注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

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