产品说明书
Sulfadiazine
 |
同义名 : | NSC 35600 |
| CAS号 : | 68-35-9 | |
| 货号 : | A293414 | |
| 分子式 : | C10H10N4O2S | |
| 纯度 : | 98% | |
| 分子量 : | 250.28 | |
| MDL号 : | MFCD00006065 | |
| 存储条件： |
粉末 Keep in dark place,Sealed in dry,Room Temperature 液体 -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 50 mg/mL(199.78 mM)，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Sulfadiazine is a bacteriostatic antibacterial agent that interferes with folic acid synthesis in susceptible bacteria. The combination of Trimethoprim and Sulfadiazine produces a synergistic effect against both Gram-positive and Gram-negative aerobic bacteria[3]. Sulfadiazine (SD) is a classic antibiotic for intracranial infection. It should be offered as an option for the patients with refractory intracranial infection, especially for patients with lower ability to pay[4]. Sulfadiazine is a sulfonamide antibiotic used for the treatment of toxoplasmosis. In 100 percent of the ulcers treated with silver sulfadiazine cream (15 patients) the bacterial counts were reduced to 10(5) or less per gram of tissue within the three-week test period, compared to 78.6 percent in those treated with saline (14 patients) and 63.6 percent in those treated with povidone-iodine solution (11 patients). Moreover, the ulcers treated with silver sulfadiazine cream responded more rapidly, with one-third showing bacterial levels of less than 10(5) within three days, and half within a week[5]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
4.00mL 0.80mL 0.40mL |
19.98mL 4.00mL 2.00mL |
39.96mL 7.99mL 4.00mL |
| 参考文献 |
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