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水杨酰胺 /Salicylamide

货号:A364818 同义名: 2-羟基苯甲酰胺 / 2-Hydroxybenzamide;o-hydroxybenzamide

Salicylamide是一种非甾体抗炎药,具有镇痛和退烧作用,能够抑制微粒体中的UDP-葡萄糖醛酸转移酶。

Salicylamide 化学结构 CAS号:65-45-2
Salicylamide 化学结构
CAS号:65-45-2
Salicylamide 3D分子结构
CAS号:65-45-2
Salicylamide 化学结构 CAS号:65-45-2
Salicylamide 3D分子结构 CAS号:65-45-2
规格 价格 库存 数量
10mM*1mL(DMSO) ¥154 咨询
25mg ¥105 咨询
500mg ¥126 咨询
1g ¥189 咨询
10g ¥252 咨询
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Salicylamide 纯度/质量文件 产品仅供科研

货号:A364818 标准纯度:
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Salicylamide 生物活性

描述 Treatment with salicylamides is associated with the inhibition of bacterial growth, which is directly linked to their capacity to inhibit sulfate reduction[1].
体内研究

Administering salicylamide leads to decreased levels of radiosulfate in maternal serum and placenta, and adversely affects the incorporation of radiosulfate into fetal skeletal glycosaminoglycans (GAGs). Additionally, salicylamide administration results in reduced calcium content in fetal limb bones, although it does not significantly impact the calcium levels in maternal serum[2].

The uptake of radiosulfate by maternal serum and liver, as well as by the fetus and placenta, is decreased following salicylamide administration, with these effects being dose-dependent. Notably, changes in radiosulfate uptake over time in the fetus and placenta induced by salicylamide are significant, even independent of the maternal serum radiosulfate levels[3].

体外研究

Treatment with salicylamides is associated with the inhibition of bacterial growth, which is directly linked to their capacity to inhibit sulfate reduction[1].

Salicylamide 参考文献

[1]Kushkevych I, et al. Activity of selected salicylamides against intestinal sulfate-reducing bacteria. Neuro Endocrinol Lett. 2015;36 Suppl 1:106-13.

[2]Halstead PK, et al. Effect of salicylamide on skeletal glycosaminoglycan sulfation and calcification in fetal rat limbs. Drug Nutr Interact. 1981;1(1):75-86.

[3]Knight E, et al. Effect of salicylamide on the placental transfer and fetal tissue distribution of sodium-35S-sulfate in the rat. J Nutr. 1978 Feb;108(2):216-25.

Salicylamide 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

7.29mL

1.46mL

0.73mL

36.46mL

7.29mL

3.65mL

72.92mL

14.58mL

7.29mL

Salicylamide 技术信息

CAS号65-45-2
分子式C7H7NO2
分子量 137.14
别名 2-羟基苯甲酰胺 ;2-Hydroxybenzamide;o-hydroxybenzamide;Urtosal;Salizell;Panithal;Eggosalil;Dropsprin;Cymidon;Benesal;Allevin;Acket
运输蓝冰
存储条件

In solvent -20°C:3-6个月-80°C:12个月

Pure form Inert atmosphere,Room Temperature

溶解度

DMSO: 105 mg/mL(765.64 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方
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