货号:A391931 同义名: Vistamycin sulfate
Ribostamycin Sulfate是一种广谱抗菌药,从Streptomyces ribosifidicus中分离得到,通过结合细菌的30S和50S核糖体亚基,抑制肽酰-tRNA从A位点到P位点的转运,从而导致mRNA的错误解码。
There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.
Type | HazMat fee for 500 gram (Estimated) |
Excepted Quantity | USD 0.00 |
Limited Quantity | USD 15-60 |
Inaccessible (Haz class 6.1), Domestic | USD 80+ |
Inaccessible (Haz class 6.1), International | USD 150+ |
Accessible (Haz class 3, 4, 5 or 8), Domestic | USD 100+ |
Accessible (Haz class 3, 4, 5 or 8), International | USD 200+ |
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描述 | Ribostamycin Sulfate is a broad-spectrum antimicrobial, inhibits bacterial protein synthesis at the level of 30S and 50S ribosomal subunit binding. The binding affinity of ribostamycin to purified bovine PDI (protein disulfide isomerase) was 319 μM (K(D) value)[3]. Moreover, MIC(90) of ribostamycin is 32 mg/L)[4]. The linear relationship of ribostamycin sulfate and kanamycin between concentration and peak height was obtained in the concentration range of 0.18-1.08 mM and 0.31-1.86 mM and the determination limit was 7. 2 nM and 46 nM respectively[5]. The Cmax in children and infants after intramuscular ribostamycin 10 mg/kg approached that in adults after an intramuscular dose of ribostamycin 500 mg. It is suggested that ribostamycin was administered in intramuscular doses of 10 to 15 mg/kg twice daily in infants and 3 times daily in children, respectively[6]. |
计算器 | ||||
存储液制备 | 1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
1.81mL 0.36mL 0.18mL |
9.05mL 1.81mL 0.90mL |
18.10mL 3.62mL 1.81mL |
CAS号 | 53797-35-6 |
分子式 | C17H36N4O14S |
分子量 | 552.551 |
别名 | Vistamycin sulfate |
运输 | 蓝冰 |
存储条件 |
液体 -20°C:3-6个月-80°C:12个月 粉末 Inert atmosphere,2-8°C |
溶解度 |
H2O: 120 mg/mL(217.17 mM),配合低频超声助溶 |
动物实验配方 |