Rhodamine 6G|PAK|for research only|Ambeed

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Rhodamine 6G {[allProObj[0].p_purity_real_show]}

货号：A1372003

Rhodamine 6G 化学结构
CAS号：989-38-8

Rhodamine 6G 3D分子结构
CAS号：989-38-8

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Rhodamine 6G 纯度/质量文件产品仅供科研

货号：A1372003 标准纯度： {[allProObj[0].p_purity_real_show]} 产品说明书

批次查询：批次纯度: COA SDS NMR HPLC CNMR LC-MS

全球学术期刊中引用的产品: • Nat. Biomed. Eng., 2024, 8, 1412-1424. Ambeed. [ A538667 , A631746 ]; • JMC, 2024. Ambeed. [ A833302 , A475501 , A341986 , A356070 ]; • BMC Cancer, 2024, 24(1): 1415. Ambeed. [ A809692 , A209020 ]; • J. Am. Soc. Mass Spectrom., 2024, 35(12): 3192-3202. Ambeed. [ A166127 , A902473 , A753371 , A961334 , A292945 , A230770 , A300620 , A1114580 , A1159765 , A206238 ]; • PloS One, 2024, 19(11): e0308060. Ambeed. [ A302917 ]; 更多 >

PAK 亚型比较

产品名称	PAK ↓ ↑	PAK1 ↓ ↑	PAK2 ↓ ↑	PAK3 ↓ ↑	PAK4 ↓ ↑	PAK5 ↓ ↑	PAK6 ↓ ↑	纯度
IPA-3	+ PAK1, IC50: 2.5 μM	+ PAK1, IC50: 2.5 μM						99%+
FRAX486	+++ PAK4, IC50: 39 nM PAK1, IC50: 14 nM	+++ PAK1, IC50: 14 nM	++ PAK2, IC50: 33 nM	++ PAK3, IC50: 39 nM	+ PAK4, IC50: 575 nM			99%+
FRAX1036	++ PAK4, Ki: 23.3 nM PAK2, Ki: 72.4 nM	++ PAK1, Ki: 23.3 nM	++ PAK2, Ki: 72.4 nM		+ PAK4, Ki: 2.4 μM			99%+
FRAX597	++++ PAK2, IC50: 13 nM PAK3, IC50: 13 nM	++++ PAK1, IC50: 8 nM	++++ PAK2, IC50: 13 nM	+++ PAK3, IC50: 19 nM				98+%
PF-3758309	++++ PAK3, IC50: 190 nM PAK6, Ki: 17.1 nM	++++ PAK1, Ki: 13.7 nM	+ PAK2, IC50: 190 nM	++ PAK3, IC50: 99 nM	+++ PAK4, Ki: 18.7 nM	+++ PAK5, Ki: 18.1 nM	+++ PAK6, Ki: 17.1 nM	99%+
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多，抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用，但抑制强度暂时没有相关数据。

Rhodamine 6G 生物活性

描述

Rhodamine dyes, known for their membrane-permeable and cationic properties, are specific to mitochondrial membrane potentials and are utilized to label mitochondria in various cell types due to their low cellular toxicity^[1].

体内研究

Mice implanted with melanoma and treated with Rhodamine 6G show increased survival rates, improved clinical parameters, and reduced tumor growth and metastasis counts. A twice-weekly regimen of 10-6M Rhodamine 6G demonstrates the most significant effects^[2].

Once introduced into the circulatory system, Rhodamine-6G marks leukocytes, enabling the observation of changes in leukocyte interactions with the endothelium through the quantification of rolling and adhering leukocytes, as well as their overall movement^[3].

体外研究

Rhodamine 6G 参考文献

[1]Kutushov M, et al. Low concentrations of Rhodamine 6G selectively destroy tumor cells and improve survival of melanoma transplanted mice. Neoplasma. 2013;60(3):262-73.

[2]Zehentbauer FM, et al. Fluorescence spectroscopy of Rhodamine 6G: concentration and solvent effects. Spectrochim Acta A Mol Biomol Spectrosc. 2014;121:147-51.

[3]Kutushov M, et al. Low concentrations of Rhodamine 6G selectively destroy tumor cells and improve survival of melanoma transplanted mice. Neoplasma. 2013;60(3):262-73.

Rhodamine 6G 实验方案

计算器

存储液制备

1mg

5mg

10mg

1 mM

5 mM

10 mM

2.09mL

0.42mL

0.21mL

10.44mL

2.09mL

1.04mL

20.88mL

4.18mL

2.09mL

Rhodamine 6G 技术信息

CAS号	989-38-8
分子式	C₂₈H₃₁ClN₂O₃
分子量	479.01

别名
运输	蓝冰

存储条件

液体 -20°C:3-6个月-80°C:12个月

粉末 Keep in dark place,Sealed in dry,Room Temperature

溶解度

DMSO: 25 mg/mL(52.19 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

H₂O: 10 mg/mL(20.88 mM)，配合低频超声，并水浴加热至45℃助溶

动物实验配方

Rhodamine 6G {[allProObj[0].p_purity_real_show]}

Rhodamine 6G 纯度/质量文件产品仅供科研

全球学术期刊中引用的产品

Rhodamine 6G 质控信息

Rhodamine 6G 生物活性

Rhodamine 6G 参考文献

Rhodamine 6G 实验方案

Rhodamine 6G 技术信息

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Rhodamine 6G {[allProObj[0].p_purity_real_show]}

Rhodamine 6G 纯度/质量文件 产品仅供科研

全球学术期刊中引用的产品

Rhodamine 6G 质控信息

Rhodamine 6G 生物活性

Rhodamine 6G 参考文献

Rhodamine 6G 实验方案

Rhodamine 6G 技术信息

最近浏览的产品

大规格询价

摩尔计算器

靶点

总药量计算器

工作液计算器

细胞研究

临床研究

确认信息

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Rhodamine 6G 纯度/质量文件产品仅供科研