Prothionamide | 2-丙基吡啶-4-硫代甲酰胺 | Protionamide | Anti-tuberculosis Agent

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丙硫异烟胺 /Prothionamide {[allProObj[0].p_purity_real_show]}

货号：A306379 同义名： 2-丙基吡啶-4-硫代甲酰胺 / Protionamide;Tebeform

Prothionamide是用于治疗麻风病和结核病的二线药物，对结核分枝杆菌具有高度有效性。

Prothionamide 化学结构
CAS号：14222-60-7

Prothionamide 3D分子结构
CAS号：14222-60-7

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Prothionamide 纯度/质量文件产品仅供科研

货号：A306379 标准纯度： {[allProObj[0].p_purity_real_show]} 产品说明书

批次查询：批次纯度: COA SDS NMR HPLC CNMR LC-MS

全球学术期刊中引用的产品: • JMC, 2024. Ambeed. [ A919389 , A918471 , A995972 ]; • Anal. Chem., 2024, 96(50): 19947-19954. Ambeed. [ A261947 , A1165388 ]; • ACS Biomater. Sci. Eng., 2024. Ambeed. [ A220462 ]; • ACS Biomater. Sci. Eng., 2024. Ambeed. [ A165235 , A110205 ]; • Pharmaceutics, 2024, 16(12): 1546. Ambeed. [ A272538 , A187261 , A691302 , A506702 ]; 更多 >

Prothionamide 生物活性

描述	Protionamide is a drug used in the treatment of tuberculosis and has also been tested for use in the treatment of leprosy.

Prothionamide 临床研究

NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点
NCT03237182	Tuberculosis, Multidrug-Resist... 展开 >>ant 收起 <<	Phase 4	Recruiting	December 2021	South Africa ... 展开 >> King Dinuzulu Hospital Recruiting Durban, Kwa-Zulu Natal, South Africa Contact: Nesri Padayatchi, MBcHB 0312604550 nesri.padayatchi@caprisa.org Contact: Resha Boodhram, BTech 0828383651 resha.boodhram@caprisa.org 收起 <<
NCT00042289	HIV Infections	Phase 4	Recruiting	September 30, 2019	-
NCT00513396	Tuberculosis, Multidrug-Resist... 展开 >>ant 收起 <<	Phase 2 Phase 3	Completed	-	-

Prothionamide 参考文献

[1]Wang F, Langley R, et al. Mechanism of thioamide drug action against tuberculosis and leprosy. J Exp Med. 2007 Jan 22;204(1):73-8.

[2]Fajardo TT, Guinto RS, et al. A clinical trial of ethionamide and prothionamide for treatment of lepromatous leprosy. Am J Trop Med Hyg. 2006 Mar;74(3):457-61.

Prothionamide 实验方案

计算器

存储液制备

1mg

5mg

10mg

1 mM

5 mM

10 mM

5.55mL

1.11mL

0.55mL

27.74mL

5.55mL

2.77mL

55.47mL

11.09mL

5.55mL

Prothionamide 技术信息

CAS号	14222-60-7
分子式	C₉H₁₂N₂S
分子量	180.27

别名	2-丙基吡啶-4-硫代甲酰胺 ;Protionamide;Tebeform;2-Propyl-4-thiocarbamoylpyridine;2-Propyl-4-pyridinecarbothioamide;1321-TH
运输	蓝冰

存储条件

In solvent -20°C:3-6个月-80°C:12个月

Pure form Inert atmosphere,Store in freezer, under -20°C

溶解方案

细胞实验：

DMSO: 105 mg/mL(582.46 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

动物实验配方

临床研究

NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点

NCT03237182	Tuberculosis, Multidrug-Resist... 展开 >>ant 收起 <<	Phase 4	Recruiting	December 2021	South Africa ... 展开 >> King Dinuzulu Hospital Recruiting Durban, Kwa-Zulu Natal, South Africa Contact: Nesri Padayatchi, MBcHB 0312604550 nesri.padayatchi@caprisa.org Contact: Resha Boodhram, BTech 0828383651 resha.boodhram@caprisa.org 收起 <<
NCT00042289	HIV Infections	Phase 4	Recruiting	September 30, 2019	-
NCT00513396	Tuberculosis, Multidrug-Resist... 展开 >>ant 收起 <<	Phase 2 Phase 3	Completed	-	-
NCT02975570	Tuberculosis Multi Drug Resist... 展开 >>ant Active 收起 <<	Phase 3	Withdrawn(The study could not ... 展开 >>be conducted since funding was not obtained.) 收起 <<	August 2022	-
NCT03057756	-		Recruiting	March 1, 2021	Gabon ... 展开 >> Centre de Recherches Médicales de Lambaréné Recruiting Lambarene, Please Select, Gabon, BP 242 Contact: Ayola A Adegnika, PhD, MD +24107406464 aadegnika@cermel.org Contact: Ronald J EDOA, MD j.ronaldedoa@cermel.org Sub-Investigator: Martin P Grobusch, PhD, MD Sub-Investigator: Susie Goulds, MD Sub-Investigator: Bertrand O Lell, MD, MSc Sub-Investigator: Marguérite Massinga Loembe, PhD Sub-Investigator: Ulysse Ateba Ngoa, MD, PhD 收起 <<
NCT02496572	-		Unknown	April 2016	Uzbekistan ... 展开 >> Outpatient clinics in three districts Nukus, Karakalpakstan, Uzbekistan 收起 <<
NCT03604848	Multidrug Resistant Tuberculos... 展开 >>is 收起 <<	Not Applicable	Not yet recruiting	August 4, 2024	China, Guangzhou ... 展开 >> The Third People's Hospital of Shenzhen City Not yet recruiting Shenzhen, Guangzhou, China Contact: Guofang Deng lalaliy@sina.com China, Heilongjiang the First Affiliated Hospital of Harbin Medical University Harbin, Heilongjiang, China China, Henan The Sixth People's Hospital of Zhengzhou Zhengzhou, Henan, China China, Jiangsu The Fifth People's Hospital of Suzhou Suzhou, Jiangsu, China China, Sichuan The Affiliated Hospital of Southwest Medical University Not yet recruiting Luzhou, Sichuan, China Contact: Fuli Huang flh905@aliyun.com China, Xinjiang Chest Hospitalof Xinjiang Uygur Autonomous Region of PRC Not yet recruiting Urumqi, Xinjiang, China Contact: Wenlong Guan 18999918582@189.cn China, Zhejaing Zhuji City People's Hospital Not yet recruiting Zhuji, Zhejaing, China Contact: Heqing Huang zjganran@163.com China, Zhejiang Hangzhou Red Cross Hospital Hangzhou, Zhejiang, China Zhejiang Provincial Center for Disease Control and Prevention Hangzhou, Zhejiang, China The Second Hospital of Yinzhou of Ningbo Ningbo, Zhejiang, China, 315040 Enze Medical Center of Taizhou CIty Not yet recruiting Taizhou, Zhejiang, China Contact: Zebao He hezb@enzemed.com The Central Hospital of Wenzhou City Not yet recruiting Wenzhou, Zhejiang, China Contact: Xiangao Jiang shijichan@163.com 收起 <<
NCT02128308	Healthy	Phase 1	Completed	-	Korea, Republic of ... 展开 >> Seoul National University Bundang Hospital Seoul, Korea, Republic of 收起 <<
NCT02409290	MDR-TB	Phase 3	Recruiting	December 2021	China ... 展开 >> Beijing Chest Hospital Not yet recruiting Beijing, China Wuhan Institute for TB control Not yet recruiting Wuhan, China Ethiopia Armauer Hanssen Research Institute Recruiting Addis Ababa, Ethiopia St. Peter's Tuberculosis Specializes Hospital Recruiting Addis Ababa, Ethiopia Georgia JSC National Center for Tuberculosis and Lung Diseases Recruiting Tbilisi, Georgia India BJ Medical College Civil Hospital Recruiting Ahmedabad, India The National Institute for Research in Tuberculosis Recruiting Chennai, India Indonesia RSUP Persahabatan Not yet recruiting Jakarta, Indonesia Moldova, Republic of Institute of Phthisiopneumology 'Chiril Draganiuc' Recruiting Chisinau, Moldova, Republic of Mongolia National Centre for Communicable Diseases Recruiting Ulaanbaatar, Mongolia South Africa King Dinizulu Hospital Recruiting Durban, South Africa Helen Joseph Hospital Recruiting Johannesburg, South Africa Sizwe Tropical Disease Hospital Active, not recruiting Johannesburg, South Africa Doris Goodwin Hospital Recruiting Pietermaritzburg, South Africa Empilweni TB Hospital Not yet recruiting Port Elizabeth, South Africa Uganda Makerere University Recruiting Kampala, Uganda Mulago National Referral Hospital Recruiting Kampala, Uganda Vietnam Pham Ngoc Thach Hospital Active, not recruiting Ho Chi Minh City, Vietnam 收起 <<
NCT02120638	Multidrug Resistant Tuberculos... 展开 >>is 收起 <<	Phase 3	Unknown	April 2016	China, Chongqing ... 展开 >> Chongqing Pulmonary Hospital Recruiting Chongqing, Chongqing, China Contact: Xiyan Zhang 593189393@qq.com China, Henan The Sixth People's Hospital of Zhengzhou Recruiting Zhengzhou, Henan, China Contact: Yu Chen chenyuhnzz@163.com China, Jiangsu The Fifth People's Hospital of Suzhou Recruiting Suzhou, Jiangsu, China Contact: Peijun Tang tangpeipei001@163.com The Fifth People's Hospital of Wuxi Recruiting Wuxi, Jiangsu, China Contact: Qinlao Ou oqinfang@163.com China, Xinjiang Xinjiang Chest Hospital Active, not recruiting Urumqi, Xinjiang, China China, Zhejiang Hangzhou Red Cross Hospital Recruiting Hangzhou, Zhejiang, China Contact: Yunfeng Sheng shengyf617@163.com The Affiliated Hospital of Hangzhou Normal University Active, not recruiting Hangzhou, Zhejiang, China The Affiliated Hospital of Luzhou Medical College Recruiting Huzhou, Zhejiang, China Contact: Fuli Huang 10111220006@fudan.edu.cn Wenling No.1 People's Hospital Active, not recruiting Taizhou, Zhejiang, China Ruian People's Hospital Recruiting Wenzhou, Zhejiang, China Contact: Dong Zhang 418022491@qq.com Zhuji People's Hospital of Zhejiang Province Recruiting Zhuji, Zhejiang, China Contact: Heqing Huang zjganran@163.com 收起 <<

丙硫异烟胺 /Prothionamide {[allProObj[0].p_purity_real_show]}

Prothionamide 纯度/质量文件产品仅供科研

全球学术期刊中引用的产品

Prothionamide 质控信息

Prothionamide 生物活性

Prothionamide 临床研究

Prothionamide 参考文献

Prothionamide 实验方案

Prothionamide 技术信息

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丙硫异烟胺 /Prothionamide {[allProObj[0].p_purity_real_show]}

Prothionamide 纯度/质量文件 产品仅供科研

全球学术期刊中引用的产品

Prothionamide 质控信息

Prothionamide 生物活性

Prothionamide 临床研究

Prothionamide 参考文献

Prothionamide 实验方案

Prothionamide 技术信息

最近浏览的产品

大规格询价

摩尔计算器

靶点

总药量计算器

工作液计算器

细胞研究

临床研究

确认信息

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