Pepsin | EC 3.4.23.1 (MS Grade) | 胃蛋白酶（猪源） | Hydrolase

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胃蛋白酶 /Pepsin {[allProObj[0].p_purity_real_show]}

货号：A448852 同义名： 胃蛋白酶（猪源） / EC 3.4.23.1 (MS Grade)

Pepsin是一种内切肽酶，将蛋白质分解为小肽和氨基酸，促进小肠的蛋白质吸收。

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Type	HazMat fee for 500 gram (Estimated)
Excepted Quantity	USD 0.00
Limited Quantity	USD 15-60
Inaccessible (Haz class 6.1), Domestic	USD 80+
Inaccessible (Haz class 6.1), International	USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic	USD 100+
Accessible (Haz class 3, 4, 5 or 8), International	USD 200+

Pepsin 化学结构
CAS号：9001-75-6

Pepsin 3D分子结构
CAS号：9001-75-6

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Pepsin 纯度/质量文件产品仅供科研

货号：A448852 标准纯度： {[allProObj[0].p_purity_real_show]} 产品说明书

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全球学术期刊中引用的产品: • Neuron, 2025. Ambeed. [ A1440350 ]; • Nature Communications, 2025, 16, 996. Ambeed. [ A111960 , A505336 ]; • JACS, 2025. Ambeed. [ A349578 , A2270125 ]; • PLoS Biol., 2025, 23(2): e3002961. Ambeed. [ A181909 ]; • Redox Rep., 2025, 30(1): 2454887. Ambeed. [ A1155014 ]; 更多 >

Pepsin 生物活性

描述

Pepsin is an endopeptidase that breaks down proteins into smaller peptides and amino acids that can be easily absorbed in the small intestine ^[1]. Pepsin is stable at pH ranges as high as pH 6. Above this pH, pepsin is rapidly irreversibly inactivated and elevation of pH of the reaction mixture to pH 8 results in complete inactivation of pepsin^[2]. Pepsin has been posited to be a reliable biological marker of EER. An immunologic pepsin assay of combined sputum and saliva was determined to be 100% sensitive and 89% specific for detection of EER (based on pH-metry), and an enzymatic test of nasal lavage fluid (100% sensitivity and 92.5% specificity) demonstrated an increased incidence of EER in patients with chronic rhinosinusitis ^[3]. Cultured hypopharyngeal epithelial (FaDu) cells were exposed to human pepsin (0.1 mg/mL) at pH 7.4 for either 1 hour or 12 hours at 37°C and both mitochondria and Golgi complexes were clearly damaged. This finding reveals a novel mechanism by which pepsin could cause cell damage, potentially even in nonacidic refluxate^[4].

Pepsin 参考文献

[1]Heda R, Toro F, Tombazzi CR. Physiology, Pepsin. [Updated 2022 May 8]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-.

[2]Piper DW, Fenton BH. pH stability and activity curves of pepsin with special reference to their clinical importance. Gut. 1965 Oct; 6(5): 506-508.

[3]Samuel TL, Johnston N. Pepsin as a Marker of Extraesophageal Reflux. Annals ofOtology. Rhinology & Laryngology 119(3):203-208.

[4]Johnston N, Well CW, Samuel TL, et al. Pepsin in Nonacidic Refluxate Can Damage Hypopharyngeal Epithelial Cells. Annals of Otology, Rhinology & Laryngology 118(9):677-685.

Pepsin 技术信息

CAS号	9001-75-6
分子式
分子量

别名	胃蛋白酶（猪源） ;EC 3.4.23.1 (MS Grade)
运输	蓝冰

存储条件

In solvent -20°C:3-6个月-80°C:12个月

Pure form Keep in dark place,Sealed in dry,2-8°C

溶解方案

动物实验配方

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浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)=质量 (g)

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胃蛋白酶 /Pepsin {[allProObj[0].p_purity_real_show]}

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胃蛋白酶 /Pepsin {[allProObj[0].p_purity_real_show]}

Pepsin 纯度/质量文件 产品仅供科研

全球学术期刊中引用的产品

Pepsin 质控信息

Pepsin 生物活性

Pepsin 参考文献

Pepsin 技术信息

最近浏览的产品

大规格询价

摩尔计算器

靶点

总药量计算器

工作液计算器

细胞研究

临床研究

确认信息

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Pepsin 纯度/质量文件产品仅供科研