There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.
Type
HazMat fee for 500 gram (Estimated)
Excepted Quantity
USD 0.00
Limited Quantity
USD 15-60
Inaccessible (Haz class 6.1), Domestic
USD 80+
Inaccessible (Haz class 6.1), International
USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic
USD 100+
Accessible (Haz class 3, 4, 5 or 8), International
PACMA 31, an irreversible and orally administered inhibitor of protein disulfide isomerase (PDI), has an IC50 of 10 μM. It covalently binds to the active site cysteines of PDI. PACMA 31 is capable of targeting tumors and significantly reduces the growth of ovarian tumors without harming normal tissues. In a dose-dependent manner, PACMA 31 at concentrations ranging from 0 to 10 μM over 24 hours markedly inhibits colony formation in OVCAR-8 cells[1].
PACMA 31 动物研究
Animal study
PACMA 31 administered intraperitoneally at doses between 20 and 200 mg/kg daily for 62 days effectively suppresses tumor growth in human ovarian cancer mouse xenograft models[1].
搜索
HazMat Fee +
