Ambeed.cn

首页 / / / / Nitrofurantoin

呋喃妥因 /Nitrofurantoin {[allProObj[0].p_purity_real_show]}

货号:A109585 同义名: NSC 2107;Macrodantin

Nitrofurantoin是一种口服活性的广谱抗菌剂,主要用于治疗尿路感染(如膀胱炎和肾脏感染),通过抑制细菌的 DNA、RNA 和细胞壁蛋白合成发挥作用。

HazMat Fee +

There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.

Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Nitrofurantoin 化学结构 CAS号:67-20-9
Nitrofurantoin 化学结构
CAS号:67-20-9
Nitrofurantoin 3D分子结构
CAS号:67-20-9
Nitrofurantoin 化学结构 CAS号:67-20-9
Nitrofurantoin 3D分子结构 CAS号:67-20-9
规格 价格 会员价 库存 数量
{[ item.pr_size ]}

{[ getRatePrice(item.pr_rmb, 1,1) ]}

{[ getRatePrice(item.pr_rmb_sale, 1,1) ]} {[ suihuo_tips(item.pr_tag_price) ]}

{[ getRatePrice(item.pr_rmb, 1,1) ]}

{[ getRatePrice(item.pr_rmb,item.pr_rate,1) ]} {[ suihuo_tips(item.pr_tag_price) ]}
{[ getRatePrice(item.pr_rmb, 1,1) ]}{[ suihuo_tips(item.pr_tag_price) ]} {[ getRatePrice(item.pr_rmb_sale, 1,1) ]} {[ getRatePrice(item.pr_rmb,item.pr_rate,item.mem_rate) ]} {[ getRatePrice(item.pr_rmb,1,item.mem_rate) ]} 现货 咨询 - +
购物车0 收藏 询单

Nitrofurantoin 纯度/质量文件 产品仅供科研

货号:A109585 标准纯度: {[allProObj[0].p_purity_real_show]}
批次查询: 批次纯度:

全球学术期刊中引用的产品

JMC, 2024. Ambeed. [ A919389 , A918471 , A995972 ]
Anal. Chem., 2024, 96(50): 19947-19954. Ambeed. [ A261947 , A1165388 ]
ACS Biomater. Sci. Eng., 2024. Ambeed. [ A220462 ]
ACS Biomater. Sci. Eng., 2024. Ambeed. [ A165235 , A110205 ]
Pharmaceutics, 2024, 16(12): 1546. Ambeed. [ A272538 , A187261 , A691302 , A506702 ]
更多 >

Nitrofurantoin 生物活性

描述 Nitrofurantoin is an old antibiotic and an important first-line oral antibiotic for the treatment of uncomplicated urinary tract infections. Nitrofurantoin is not a uniform product -crystal sizes of nitrofurantoin, and therefore pharmacokinetic properties, differ significantly by product[3]. A broad spectrum of liver toxicity associated with nitrofurantoin use has been reported, ranging from acute hepatitis, granulomatous reaction, cholestasis, or autoimmune-mediated hepatitis to chronic active hepatitis that could lead to cirrhosis or death[4]. On the basis of urinary nitrofurantoin excretion determined after oral and intravenous drug administration, orally administered nitrofurantoin in a suitable dosage form is well absorbed[5].

Nitrofurantoin 临床研究

NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT03466502 Clostridium Difficile Infectio... 展开 >>n 收起 << Phase 4 Enrolling by invitation March 2019 United States, Nevada ... 展开 >> Renown Regional Medical Center Reno, Nevada, United States, 89502 收起 <<
NCT01349738 - Unknown May 2013 United States, California ... 展开 >> Scripps Green Hospital La Jolla, California, United States, 92037 收起 <<
NCT03508921 Overactive Bladder ... 展开 >> Urinary Tract Infections 收起 << Phase 4 Recruiting September 1, 2019 United States, Tennessee ... 展开 >> Vanderbilt University Medical Center Recruiting Nashville, Tennessee, United States, 37232 收起 <<

Nitrofurantoin 参考文献

[1]Yeo SJ, Jin C, et al. In Vitro and in Vivo Effects of Nitrofurantoin on Experimental Toxoplasmosis. Korean J Parasitol. 2016 Apr;54(2):155-61.

[2]Martin WJ 2nd. Nitrofurantoin: evidence for the oxidant injury of lung parenchymal cells. Am Rev Respir Dis. 1983 Apr;127(4):482-6.

[3]Wijma RA, Fransen F, Muller AE, Mouton JW. Optimizing dosing of nitrofurantoin from a PK/PD point of view: What do we need to know? Drug Resist Updat. 2019 Mar;43:1-9. doi: 10.1016/j.drup.2019.03.001. Epub 2019 Mar 20. PMID: 30947111.

[4]Sakaan SA, Twilla JD, Usery JB, Winton JC, Self TH. Nitrofurantoin-induced hepatotoxicity: a rare yet serious complication. South Med J. 2014 Feb;107(2):107-13. doi: 10.1097/SMJ.0000000000000059. PMID: 24926677.

[5]Conklin JD. The pharmacokinetics of nitrofurantoin and its related bioavailability. Antibiot Chemother (1971). 1978;25:233-52. doi: 10.1159/000401065. PMID: 352255.

Nitrofurantoin 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

4.20mL

0.84mL

0.42mL

20.99mL

4.20mL

2.10mL

41.99mL

8.40mL

4.20mL

Nitrofurantoin 技术信息

CAS号67-20-9
分子式C8H6N4O5
分子量 238.157
别名 NSC 2107;Macrodantin;Nitrofurantoin, Macrobid, Macrodantin, 5-Nitrofurantoin, Furadantine, Furadonine;NSC 44150;Furadonine;Furadantine
运输蓝冰
存储条件

In solvent -20°C:3-6个月-80°C:12个月

Pure form Keep in dark place,Inert atmosphere,Room temperature

溶解度

DMSO: 105 mg/mL(440.89 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方
Ambeed 相关网站 Ambeed.cn Ambeed.com
Ambeed
关于我们
联系我们
资讯中心
网站地图
产品手册
  • 批次文件查询
  • 客户支持
    技术支持
    专业术语
    缩略词释义
    质量手册
    产品咨询
    计算器
    活动政策
    订购方法
    积分商城
    活动声明
    联系我们
    400-920-2911 sales@ambeed.cn tech@ambeed.cn
    Ambeed 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务,不为任何个人或者非科研性质用途提供服务。