柚皮素 /Naringenin
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货号：A433484
同义名：
NSC 34875;S-Dihydrogenistein
Naringenin could suppess ERK2 activity and decrease stability of FRA1. It is a predominant flavanone derived from plant food with antioxidant effect.
Naringenin 化学结构
Naringenin 3D分子结构
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Naringenin 纯度/质量文件 产品仅供科研
货号：A433484
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Naringenin 质控信息
Naringenin 生物活性
描述
Naringenin, a citrus flavonoid that possesses various biological activities, possesses a broad range of biological and pharmacological activities. Naringenin (50 mg/kg) inhibits both inflammatory pain and neurogenic inflammation[3] [4] [5]
Naringenin 参考文献
[1] Ortiz-Andrade RR, Sanchez-Salgado JC, et al. Antidiabetic and toxicological evaluations of naringenin in normoglycaemic and NIDDM rat models and its implications on extra-pancreatic glucose regulation. Diabetes Obes Metab. 2008 Nov;10(11):1097-104.
[2] Guengerich FP, Kim DH. In vitro inhibition of dihydropyridine oxidation and aflatoxin B1 activation in human liver microsomes by naringenin and other flavonoids. Carcinogenesis. 1990 Dec;11(12):2275-9.
[3] Pinho-Ribeiro FA, Zarpelon AC, Fattori V, Manchope MF, Mizokami SS, Casagrande R, Verri WA Jr. Naringenin reduces inflammatory pain in mice. Neuropharmacology. 2016 Jun;105:508-519. doi: 10.1016/j.neuropharm.2016.02.019. Epub 2016 Feb 18. PMID: 26907804.
[4] Wang Q, Ou Y, Hu G, Wen C, Yue S, Chen C, Xu L, Xie J, Dai H, Xiao H, Zhang Y, Qi R. Naringenin attenuates non-alcoholic fatty liver disease by down-regulating the NLRP3/NF-κB pathway in mice. Br J Pharmacol. 2020 Apr;177(8):1806-1821. doi: 10.1111/bph.14938. Epub 2020 Jan 30. PMID: 31758699; PMCID: PMC7070172.
[5] Zeng W, Jin L, Zhang F, Zhang C, Liang W. Naringenin as a potential immunomodulator in therapeutics. Pharmacol Res. 2018 Sep;135:122-126. doi: 10.1016/j.phrs.2018.08.002. Epub 2018 Aug 3. PMID: 30081177.
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Naringenin 实验方案
计算器
摩尔计算器
总药量计算器
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1mg
5mg
10mg
1 mM
5 mM
10 mM
3.67mL
0.73mL
0.37mL
18.37mL
3.67mL
1.84mL
36.73mL
7.35mL
3.67mL
Naringenin 技术信息
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