Ambeed 大中华区 CN | ZH

中文 - ZH English - EN

Ambeed.cn

搜索

关键字搜索批量搜索

首页 收藏 购物车0
首页 /
抑制剂/激动剂
药物研究 囊泡
/
小分子阳性药
神经信号通路 外泌体
/
SSRIs
神经递质
/ Milnacipran HCl

盐酸米那普仑 /Milnacipran HCl {[allProObj[0].p_purity_real_show]}

货号：A139696 同义名： 米那普仑盐酸盐 / Milnacipran (hydrochloride);F 2207

Milnacipran HCl is an inhibitor of serotonin-norepinephrine reuptake that can be used to treat fibromyalgia.

HazMat Fee +

There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.

Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Milnacipran HCl 化学结构 CAS号：101152-94-7
Milnacipran HCl 化学结构
CAS号：101152-94-7
Milnacipran HCl 3D分子结构
CAS号：101152-94-7
Milnacipran HCl 化学结构 CAS号：101152-94-7
Milnacipran HCl 3D分子结构 CAS号：101152-94-7
规格 价格 会员价 库存 数量
{[ item.pr_size ]}

{[ getRatePrice(item.pr_rmb, 1,1) ]}

{[ getRatePrice(item.pr_rmb_sale, 1,1) ]} {[ suihuo_tips(item.pr_am, item.pr_size) ]}

{[ getRatePrice(item.pr_rmb, 1,1) ]}

{[ getRatePrice(item.pr_rmb,item.pr_rate,1) ]} {[ suihuo_tips(item.pr_am, item.pr_size) ]} 		{[ getRatePrice(item.pr_rmb, 1,1) ]}{[ suihuo_tips(item.pr_am, item.pr_size) ]} {[ getRatePrice(item.pr_rmb_sale, 1,1) ]} {[ getRatePrice(item.pr_rmb,item.pr_rate,item.mem_rate) ]} {[ getRatePrice(item.pr_rmb,1,item.mem_rate) ]} 现货 咨询 - +
购物车0 收藏 询单

Milnacipran HCl 纯度/质量文件 产品仅供科研

货号：A139696 标准纯度： {[allProObj[0].p_purity_real_show]}
批次查询： 批次纯度:

全球学术期刊中引用的产品

• Nat. Biomed. Eng., 2024, 8, 1412-1424. Ambeed. [ A538667 , A631746 ]
• JMC, 2024. Ambeed. [ A833302 , A475501 , A341986 , A356070 ]
• BMC Cancer, 2024, 24(1): 1415. Ambeed. [ A809692 , A209020 ]
• J. Am. Soc. Mass Spectrom., 2024, 35(12): 3192-3202. Ambeed. [ A166127 , A902473 , A753371 , A961334 , A292945 , A230770 , A300620 , A1114580 , A1159765 , A206238 ]
• PloS One, 2024, 19(11): e0308060. Ambeed. [ A302917 ]
更多 >

Milnacipran HCl 生物活性

描述 Major depressive disorder (MDD) is a debilitating disease that is characterized by depressed mood, diminished interests, impaired cognitive function and vegetative symptoms, such as disturbed sleep or appetite[3]. (1S-cis)-Milnacipran Hydrochloride is the latest antidepressants approved for the treatment of MDD. It acts through an increased serotonergic activity in the central nervous system by inhibiting the reuptake of serotonin (5-HT). In addition to the SSRI activity, (1S-cis)-Milnacipran Hydrochloride is also a norepinephrine reuptake inhibitor[4]. In seven randomised, double-blind clinical trials, levomilnacipran is generally more effective than placebo for the treatment of MDD in the short-term. Preliminary evidence suggests that levomilnacipran extended release may be effective in improving not only depressive symptoms but also symptoms related to functioning (social life, work, and family life)[5].

Milnacipran HCl 临床研究

NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT00605917 - Completed - -
NCT00605917 - Completed - -
NCT00605865 - Completed - -

Milnacipran HCl 参考文献

[1]Maj J, Rogoz Z, et al. Pharmacological effects of milnacipran, a new antidepressant, given repeatedly on the alpha1-adrenergic and serotonergic 5-HT2A systems. J Neural Transm (Vienna). 2000;107(11):1345-59.

[2]Moret C, Charveron M, et al. Biochemical profile of midalcipran (F 2207), 1-phenyl-1-diethyl-aminocarbonyl-2-aminomethyl-cyclopropane (Z) hydrochloride, a potential fourth generation antidepressant drug. Neuropharmacology. 1985 Dec;24(12):1211-9.

[3]Otte C, Gold SM, Penninx BW, et al. Major depressive disorder. Nat Rev Dis Primers. 2016;2:16065

[4]Wagner G, Schultes MT, Titscher V, Teufer B, Klerings I, Gartlehner G. Efficacy and safety of levomilnacipran, vilazodone and vortioxetine compared with other second-generation antidepressants for major depressive disorder in adults: A systematic review and network meta-analysis. J Affect Disord. 2018;228:1‐12

[5]Bruno A, Morabito P, Spina E, Muscatello MR. The Role of Levomilnacipran in the Management of Major Depressive Disorder: A Comprehensive Review. Curr Neuropharmacol. 2016;14(2):191‐199

Milnacipran HCl 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.54mL

0.71mL

0.35mL

17.68mL

3.54mL

1.77mL

35.36mL

7.07mL

3.54mL

Milnacipran HCl 技术信息

CAS号101152-94-7
分子式C15H23ClN2O
分子量 282.809
别名 米那普仑盐酸盐 ;Milnacipran (hydrochloride);F 2207;Milnacipran hydrochloride
运输蓝冰
存储条件

液体 -20°C:3-6个月-80°C:12个月

粉末 Inert atmosphere,Room Temperature
溶解度

DMSO: 50 mg/mL(176.8 mM)，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

H2O: 100 mg/mL(353.6 mM)
动物实验配方

PO 0.5% CMC-Na 50 mg/mL clear

Tags: Milnacipran | 101152-94-7 | Serotonin Transporter | 5-HTT | Serotonin Transporter Inhibitor | Neuronal Signaling | Serotonin Transporter | 仅供科研使用 | AmBeed-信号通路专用抑制剂 | Milnacipran HCl 纯度/质量文件 | Milnacipran HCl 生物活性 | Milnacipran HCl 临床数据 | Milnacipran HCl 参考文献 | Milnacipran HCl 实验方案 | Milnacipran HCl 技术信息

Ambeed 相关网站 Ambeed.cn Ambeed.com
Ambeed
关于我们
联系我们
资讯中心
网站地图
产品手册
  • 批次文件查询
    • 客户支持
    技术支持
    专业术语
    缩略词释义
    质量手册
    产品咨询
    计算器
    活动政策
    订购方法
    积分商城
    活动声明
    联系我们
    400-920-2911 sales@ambeed.cn tech@ambeed.cn
    Ambeed 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质用途提供服务。

    尊敬的 Ambeed 客户您好，
    请您选择所在区域，我们将转接对应客服为您服务！

    热门区域

    A

    B

    C

    F

    G

    H

    J

    L

    N

    Q

    S

    T

    X

    Y

    Z

    热 A B C F G H J L N Q S T X Y Z