Lipofermata
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货号：A1145370
Lipofermata is an inhibitor of fatty acid transport (FATP) with IC50 of 4.84 μM in Caco-2 cells.
Lipofermata 化学结构
Lipofermata 3D分子结构
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Lipofermata 纯度/质量文件 产品仅供科研
货号：A1145370
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Lipofermata 质控信息
Lipofermata 生物活性
描述
Lipofermata is an inhibitor of fatty acid transport (FATP) with IC50 of 4.84 μM in Caco-2 cells[2] [3] [4]
Lipofermata 参考文献
[2] Ahowesso C, Black PN, Saini N, Montefusco D, Chekal J, Malosh C, Lindsley CW, Stauffer SR, DiRusso CC. Chemical inhibition of fatty acid absorption and cellular uptake limits lipotoxic cell death. Biochem Pharmacol. 2015 Nov 1;98(1):167-81
[3] Kim JL, Mestre B, Malitsky S, Itkin M, Kupervaser M, Futerman AH. Fatty acid transport protein 2 interacts with ceramide synthase 2 to promote ceramide synthesis. J Biol Chem. 2022 Feb 15:101735
[4] Zhang M, Di Martino JS, Bowman RL, Campbell NR, Baksh SC, Simon-Vermot T, Kim IS, Haldeman P, Mondal C, Yong-Gonzales V, Abu-Akeel M, Merghoub T, Jones DR, Zhu XG, Arora A, Ariyan CE, Birsoy K, Wolchok JD, Panageas KS, Hollmann T, Bravo-Cordero JJ, White RM. Adipocyte-Derived Lipids Mediate Melanoma Progression via FATP Proteins. Cancer Discov. 2018 Aug;8(8):1006-1025
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Lipofermata 实验方案
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总药量计算器
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存储液制备
1mg
5mg
10mg
1 mM
5 mM
10 mM
2.78mL
0.56mL
0.28mL
13.88mL
2.78mL
1.39mL
27.76mL
5.55mL
2.78mL
Lipofermata 技术信息
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