Lactate (Lactic acid) sodium is produced as a result of glycogenolysis and glycolysis[1]. This organic salt is primarily utilized as a buffer and pH adjuster in injection solutions. Lactate sodium is metabolizable by the body into sodium bicarbonate, which subsequently raises the blood pH. It is applied in medical treatments to ameliorate conditions like metabolic acidosis and hypovolemic states. In pharmaceutical formulations, Lactate sodium is commonly combined with sodium chloride, glucose, and other substances to create solutions such as normal saline or compound liquid for intravenous injections[2].[3].[4].[5]. Lactate sodium also exhibits antimicrobial properties, making it useful as a food preservative[6].
体外研究
Additionally, hypertonic Lactate sodium solution has been shown to enhance cognitive function in rats suffering from traumatic brain injury (TBI). This solution not only reduces intracranial pressure (ICP) but also boosts cerebral blood flow through the dilation of arterioles[2].[3].
Moreover, Lactate sodium has been found to inhibit the growth of various spoilage microorganisms, including aerobic and psychrophilic bacteria, Pseudomonas, lactic acid bacteria, and Enterobacteriaceae, which underscores its broader antimicrobial efficacy[6].
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