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Lactate sodium

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Chemical Structure| 72-17-3 同义名 : 2-羟基丙酸钠 ;Lactic acid sodium
CAS号 : 72-17-3
货号 : A128732
分子式 : C3H5NaO3
纯度 : (60% in Water)
分子量 : 112.06
MDL号 : MFCD00065400
存储条件：

粉末 Sealed in dry,Room Temperature

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(937 mM)，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

H2O: 150 mg/mL(1338.57 mM)
动物实验配方：
生物活性
描述 Lactate (Lactic acid) sodium is produced as a result of glycogenolysis and glycolysis[1]. This organic salt is primarily utilized as a buffer and pH adjuster in injection solutions. Lactate sodium is metabolizable by the body into sodium bicarbonate, which subsequently raises the blood pH. It is applied in medical treatments to ameliorate conditions like metabolic acidosis and hypovolemic states. In pharmaceutical formulations, Lactate sodium is commonly combined with sodium chloride, glucose, and other substances to create solutions such as normal saline or compound liquid for intravenous injections[2].[3].[4].[5]. Lactate sodium also exhibits antimicrobial properties, making it useful as a food preservative[6].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

8.92mL

1.78mL

0.89mL

44.62mL

8.92mL

4.46mL

89.24mL

17.85mL

8.92mL
参考文献

[1]Brooks GA. Lactate: link between glycolytic and oxidative metabolism. Sports Med. 2007;37(4-5):341-3.

[2]Ichai C, et al. Sodium lactate versus mannitol in the treatment of intracranial hypertensive episodes in severe traumatic brain-injured patients. Intensive Care Med. 2009 Mar;35(3):471-9.

[3]Rice AC, et al. Lactate administration attenuates cognitive deficits following traumatic brain injury. Brain Res. 2002 Feb 22;928(1-2):156-9.

[4]Hospira, Inc. (November 2004). "Sodium Lactate (sodium lactate) Injection, Solution, Concentrate". DailyMed. U.S. National Library of Medicine. Archived from the original on 2014-01-04. Retrieved 2012-08-16.

[5]Forsythe SM, et al. Sodium bicarbonate for the treatment of lactic acidosis. Chest. 2000 Jan;117(1):260-7.

[6]Sallam KI. Antimicrobial and antioxidant effects of sodium acetate, sodium lactate, and sodium citrate in refrigerated sliced salmon. Food Control. 2007 May;18(5):566-575.