L-Carnitine hydrochloride ((R)-Carnitine hydrochloride), a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine hydrochloride functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine hydrochloride is an antioxidant. L-Carnitine hydrochloride can ameliorate metabolic imbalances in many inborn errors of metabolism.
L-Carnitine hydrochloride ((R)-Carnitine hydrochloride) is a highly polar, small zwitterion essential as a cofactor in the mitochondrial β-oxidation pathway. It facilitates the transport of long-chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. Moreover, L-Carnitine hydrochloride serves as an antioxidant and has been shown to ameliorate metabolic imbalances in various inborn errors of metabolism[1].[2].[3].
体内研究
In a chronic murine asthma model, L-Carnitine hydrochloride administered intraperitoneally (i.p.) at doses of 125 and 250 mg/kg exhibits a pronounced bronchodilator effect and reduces urinary LTE4 excretion[2].
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