D-Glutamic Acid | (R)-2-氨基戊二酸 | NSC 77686 | Endogenous Metabolite

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D-谷氨酸 /H-D-Glu-OH {[allProObj[0].p_purity_real_show]}

货号：A210714 同义名： (R)-2-氨基戊二酸 / NSC 77686;Glutamic Acid

D-glutamic acid is the enantiomer of L- glutamic acid which is widely used in pharmaceuticals. It is also an essential constituent of bacterial peptidoglycan structure.

H-D-Glu-OH 化学结构
CAS号：6893-26-1

H-D-Glu-OH 3D分子结构
CAS号：6893-26-1

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H-D-Glu-OH 纯度/质量文件产品仅供科研

货号：A210714 标准纯度： {[allProObj[0].p_purity_real_show]} 产品说明书

批次查询：批次纯度: COA SDS NMR HPLC CNMR LC-MS

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H-D-Glu-OH 生物活性

描述

D-glutamic acid is prevalent in mammals, including humans, currently considered potential new physiologically active agents or biomarkers. D-glutamic acid is garnering interest for its role in modulating neuronal transmission and hormone secretion. In mammals, it is exclusively metabolized by the enzyme D-aspartate oxidase.^[1]. At a concentration of 4 mg/mL, D-glutamic acid reduces the binding of IgE to peanuts by 75%, whereas D-Asp do not exhibit any inhibitory effect^[2].

H-D-Glu-OH 动物研究

Animal study

Upon intraperitoneal administration, L-glutamate undergoes metabolism through a-ketoglutarate, while D-glutamate is transformed into n-pyrrolidone carboxylic acid. The second carbon atom in both D- and L-glutamate forms the methyl group of acetate within the cecum. The enzymatic conversion of D-glutamic acid to n-pyrrolidone carboxylic acid is facilitated by both the liver and kidney in rats^[3].

H-D-Glu-OH 参考文献

[1]Han H, et al. Changes in D-aspartic acid and D-glutamic acid levels in the tissues and physiological fluids of mice with various D-aspartate oxidase activities. J Pharm Biomed Anal. 2015 Dec 10;116:47-52.

[2]Chung SY, et al. IgE binding to peanut allergens is inhibited by combined D-aspartic and D-glutamic acids. Food Chem. 2015 Jan 1;166:248-53.

[3]Wilson W, et al. The metabolism of D- and L- glutamic acid in the rat. J Biol Chem. 1961 Feb;236:365-9.

H-D-Glu-OH 实验方案

计算器

存储液制备

1mg

5mg

10mg

1 mM

5 mM

10 mM

6.80mL

1.36mL

0.68mL

33.98mL

6.80mL

3.40mL

67.97mL

13.59mL

6.80mL

H-D-Glu-OH 技术信息

CAS号	6893-26-1
分子式	C₅H₉NO₄
分子量	147.129

别名	(R)-2-氨基戊二酸 ;NSC 77686;Glutamic Acid;(R)-Glutamic acid
运输	蓝冰

存储条件

液体 -20°C:3-6个月-80°C:12个月

粉末 Keep in dark place,Sealed in dry,Room Temperature

溶解度

H₂O: 12 mg/mL(81.56 mM)，配合低频超声，并调节pH至3

动物实验配方

摩尔计算器

计算溶液所需的质量，体积或浓度。 Ambeed 摩尔浓度计算器基于以下方程式：

浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)=质量 (g)

浓度

体积

分子量

质量

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全球学术期刊中引用的产品

H-D-Glu-OH 质控信息

H-D-Glu-OH 生物活性

H-D-Glu-OH 动物研究

H-D-Glu-OH 参考文献

H-D-Glu-OH 实验方案

H-D-Glu-OH 技术信息

最近浏览的产品

大规格询价

摩尔计算器

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总药量计算器

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