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H-D-Glu-OH

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Chemical Structure| 6893-26-1 同义名 : (R)-2-氨基戊二酸 ;NSC 77686;Glutamic Acid;(R)-Glutamic acid
CAS号 : 6893-26-1
货号 : A210714
分子式 : C5H9NO4
纯度 : 98%
分子量 : 147.129
MDL号 : MFCD00063112
存储条件:

粉末 Keep in dark place,Sealed in dry,Room Temperature

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

H2O: 12 mg/mL(81.56 mM),配合低频超声,并调节pH至3

动物实验配方:
生物活性
描述 D-glutamic acid is prevalent in mammals, including humans, currently considered potential new physiologically active agents or biomarkers. D-glutamic acid is garnering interest for its role in modulating neuronal transmission and hormone secretion. In mammals, it is exclusively metabolized by the enzyme D-aspartate oxidase.[1]. At a concentration of 4 mg/mL, D-glutamic acid reduces the binding of IgE to peanuts by 75%, whereas D-Asp do not exhibit any inhibitory effect[2].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

6.80mL

1.36mL

0.68mL

33.98mL

6.80mL

3.40mL

67.97mL

13.59mL

6.80mL

参考文献

[1]Han H, et al. Changes in D-aspartic acid and D-glutamic acid levels in the tissues and physiological fluids of mice with various D-aspartate oxidase activities. J Pharm Biomed Anal. 2015 Dec 10;116:47-52.

[2]Chung SY, et al. IgE binding to peanut allergens is inhibited by combined D-aspartic and D-glutamic acids. Food Chem. 2015 Jan 1;166:248-53.

[3]Wilson W, et al. The metabolism of D- and L- glutamic acid in the rat. J Biol Chem. 1961 Feb;236:365-9.