Ginsenoside Rg1/人参皂苷Rg1
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货号：A100956
同义名：
人参皂甙 Rg1
/ Panaxoside Rg1; Panaxoside A
Ginsenoside Rg1是从人参根中提取的天然产物，是一种功能性糖皮质激素受体 (GR) 配体，能增强胰岛素受体生成，促进血管生成和伤口愈合，舒张血管并降低血压，且作为一种植物雌激素具有类似雌激素的活性。
Ginsenoside Rg1/人参皂苷Rg1 化学结构
Ginsenoside Rg1/人参皂苷Rg1 3D分子结构
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Ginsenoside Rg1/人参皂苷Rg1 纯度/质量文件 产品仅供科研
货号：A100956
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Ginsenoside Rg1/人参皂苷Rg1 质控信息
Ginsenoside Rg1/人参皂苷Rg1 生物活性
描述
Ginsenoside Rg1, one of the most notable active components of Panax ginseng, has anti-inflammatory actions. In vitro , ginsenoside Rg1 functioned to HK-2 cells in a dose-dependent manner, and the 150 μM dose exhibited the most protective functions. Ginsenoside Rg1 protects HK-2 cells against LPS-induced inflammation and apoptosis[3] [4] In vivo , Ginsenoside Rg1 treatment (10 mg/mL) lameliorated depression-like behaviors and reduced chronic unpredictable mild stress exposure-Induced microglial activation and inflammatory cytokine expression within the ventral medial prefrontal cortex[5]
Ginsenoside Rg1/人参皂苷Rg1 参考文献
[1] He J, Li YL. Ginsenoside Rg1 downregulates the shear stress induced MCP-1 expression by inhibiting MAPK signaling pathway. Am J Chin Med. 2015;43(2):305-17.
[2] Liu QF, Deng ZY, et al. Ginsenoside Rg1 protects chronic cyclosporin a nephropathy from tubular cell apoptosis by inhibiting endoplasmic reticulum stress in rats. Transplant Proc. 2015 Mar;47(2):566-9.
[3] Ni XJ, Xu ZQ, Jin H, Zheng SL, Cai Y, Wang JJ. Ginsenoside Rg1 protects human renal tubular epithelial cells from lipopolysaccharide-induced apoptosis and inflammation damage. Braz J Med Biol Res. 2017 Dec 11;51(2):e6611. doi: 10.1590/1414-431X20176611. Retraction in: Braz J Med Biol Res. 2020;53(10):e6611retraction. PMID: 29267498; PMCID: PMC5731327.
[4] Guan S, Xu W, Han F, Gu W, Song L, Ye W, Liu Q, Guo X. Ginsenoside Rg1 Attenuates Cigarette Smoke-Induced Pulmonary Epithelial-Mesenchymal Transition via Inhibition of the TGF-β1/Smad Pathway. Biomed Res Int. 2017;2017:7171404. doi: 10.1155/2017/7171404. Epub 2017 Aug 13. PMID: 29104873; PMCID: PMC5572594.
[5] Fan C, Song Q, Wang P, Li Y, Yang M, Yu SY. Neuroprotective Effects of Ginsenoside-Rg1 Against Depression-Like Behaviors via Suppressing Glial Activation, Synaptic Deficits, and Neuronal Apoptosis in Rats. Front Immunol. 2018 Dec 7;9:2889. doi: 10.3389/fimmu.2018.02889. PMID: 30581440; PMCID: PMC6292928.
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Ginsenoside Rg1/人参皂苷Rg1 实验方案
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1mg
5mg
10mg
1 mM
5 mM
10 mM
1.25mL
0.25mL
0.12mL
6.24mL
1.25mL
0.62mL
12.48mL
2.50mL
1.25mL
Ginsenoside Rg1/人参皂苷Rg1 技术信息
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