Famciclovir is the prodrug of penciclovir, a guanosine analogue that inhibits viruses of the alpha sub-family of the Herpesviridae, as well as hepatitis B virus. It is indicated for management of mucocutaneous herpes simplex virus disease and acute herpes zoster, and has been investigated for management of hepatitis B virus infection[3]. Famciclovir (Famvir) is the oral prodrug of penciclovir, an agent that has demonstrated antiviral activity against herpes simplex viruses, type 1 (HSV-1) and 2 (HSV-2) [which cause orolabial and/or genital herpes simplex], and against varicella zoster virus (VZV) [a reactivation of which leads to herpes zoster][4]. Famciclovir is an effective treatment of immunocompetent patients with acute herpes zoster (shingles) caused by VZV(varicella zoster virus). Famciclovir has therapeutic efficacy similar to that of oral aciclovir (acyclovir) in attenuating the acute signs and symptoms of infection (including pain during the acute phase of infection). In immunocompetent patients with recurrent genital herpes infection, suppressive treatment with oral famciclovir effectively prolonged the time to recurrence of symptomatic episodes of infection compared with placebo. In addition, famciclovir significantly reduced the duration of viral shedding, accelerated healing of genital herpes lesions and reduced the duration of symptoms[5].
United States, Missouri
... 展开 >>
Gateway Medical Research, Inc.
St. Charles, Missouri, United States, 63301
Canada, Ontario
Ba Research Co.
Toronto, Ontario, Canada, M1P2X4 收起 <<
United States, New York
... 展开 >>
Columbia University Medical Center
New York, New York, United States, 10032
Costa Rica
Novartis Investigational Site
San Jose, Costa Rica
Guatemala
Novartis Investigational Site
Cuidad de Guatemala, Guatemala
Panama
Novartis Investigational Site
Ciudad de Panama, Panama
Novartis Investigational Site
David, Chiriqui, Panama 收起 <<
United States, Alabama
... 展开 >>
University of Alabama at Birmingham
Birmingham, Alabama, United States, 35294
United States, Florida
Orlando Clinical Research Center
Orlando, Florida, United States, 32809
United States, Indiana
IU Center for Clinical STD Research
Indianapolis, Indiana, United States, 46202
United States, North Carolina
UNC Clinical Research - Raleigh
Raleigh, North Carolina, United States, 27607
United States, Oklahoma
Lynne Health Science Institute
Oklahoma City, Oklahoma, United States, 73112
United States, Oregon
Westover Heights Clinic
Portland, Oregon, United States, 97210
United States, Washington
University of Washington - Virology Research Clinic
Seattle, Washington, United States, 98122 收起 <<
Brazil
... 展开 >> Centro de Medicina Reprodutiva Dr Carlos Isaia Filho Ltda
Porto Alegre, RS, Brazil
Hospital de Clínicas de Porto Alegre
Porto Alegre, RS, Brazil
SPVita
Braganca Paulista, SP, Brazil
Caep Centro Avancado de Estudos E Pesquisas Ltda
Campinas, SP, Brazil
CEMICAMP - Centro de Pesquisas em Saúde Reprodutiva de Campinas
Campinas, SP, Brazil
CECIP - Centro de Estudos Clínicos do Interior Paulista
Jau, SP, Brazil
Hospital das Clínicas da Faculdade de Medicina de Ribeirao Preto da Universidade de Sao Paulo
Ribeirao Preto, SP, Brazil, 14048900
Instituto Sirio Libanes de Ensino e Pesquisa
Sao Paulo, SP, Brazil, 01308-060
Afip - Associacao Fundo de Incentivo A Psicofarmacologia
Sao Paulo, SP, Brazil 收起 <<
United States, Missouri
... 展开 >>
Gateway Medical Research, Inc.
St. Charles, Missouri, United States, 63301
Canada, Ontario
Ba Research Co.
Toronto, Ontario, Canada, M1P2X4 收起 <<
Brazil
... 展开 >> Centro de Medicina Reprodutiva Dr Carlos Isaia Filho
Recruiting
Porto Alegre, RS, Brazil
Contact: Carlos Isaia Filho, MD 55 51 3222-8180
Principal Investigator: Carlos Isaia Filho, MD
Loema
Recruiting
Campinas, SP, Brazil, 13010001
Contact: Fabio R Santos, MD contato@loemaipc.com.br
Principal Investigator: Fabio R Santos, MD
CECIP Centro de Estudos Clínicos do Interior Paulista
Recruiting
Jau, SP, Brazil
Contact: Paula U. Tokunaga, MD cecipjau@gmail.com
Principal Investigator: Paula U. Tokunaga, MD
Afip - Associacao Fundo de Incentivo A Pesquisa
Recruiting
Sao Paulo, SP, Brazil
Contact: Jane Tomimori, MD 55 11 5908 7081
Principal Investigator: Jane Tomimori, MD
Allergisa
Recruiting
Campinas, São Paulo, Brazil
Contact: Andre L Vergnanini, MD +55193789-8600
Principal Investigator: André L Vergnanini, MD 收起 <<
United States, Alabama
... 展开 >>
University of Alabama at Birmingham
Birmingham, Alabama, United States, 35233-1711
United States, Colorado
The Children's Hospital
Denver, Colorado, United States, 80218
United States, Illinois
Children's Memorial Hospital
Chicago, Illinois, United States, 60614
United States, Kentucky
Kosair Charities Pediatric Clinical Research Unit
Louisville, Kentucky, United States, 40202-3830
United States, New York
Columbia University Medical Center
New York, New York, United States, 10032
State University of New York at
Stony Brook, New York, United States, 11794-3362
United States, North Carolina
Duke University Medical Center
Durham, North Carolina, United States, 27710
United States, Ohio
Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, United States, 45229-3039
University Hospitals of Cleveland
Cleveland, Ohio, United States, 44106
United States, Texas
Children's Medical Center of Dallas
Dallas, Texas, United States, 75235
Baylor College of Medicine/Texas Children's Hospital
Houston, Texas, United States, 77030
Panama
Panama Minister of Health
Ciudad de David, Chiriqui, Panama
Panama Minister of Health
Ciudad de Panama, Panama 收起 <<
United States, California
... 展开 >>
Women's Health Care at Frost Street
San Diego, California, United States
United States, Illinois
Children's Memorial Hospital
Chicago, Illinois, United States, 60614
United States, Indiana
Medisphere Medical Research Center, LLC
Evansville, Indiana, United States, 47714
United States, Missouri
Clayton Medical Research
St. Louis, Missouri, United States, 63117
United States, New York
Rochester Clinical Research, Inc.
Rochester, New York, United States
United States, Ohio
Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, United States, 45229
University Hospitals Case Medical Center
Cleveland, Ohio, United States, 44106
United States, Oregon
Westover Heights Clinic
Portland, Oregon, United States, 97210
United States, Pennsylvania
Primary Physicians Research, Inc
Pittsburgh, Pennsylvania, United States
United States, Texas
Texas Children's Hospital
Houston, Texas, United States, 77030
R/D Clinical Research, Inc
Lake Jackson, Texas, United States, 77566
R/D Clinical Research
Lake Jackson, Texas, United States, 77566 收起 <<
United States, Alabama
... 展开 >>
Pediatric Infectious Disease Of University of Alabama
Birmingham, Alabama, United States
United States, Illinois
Children's Memorial Hospital Chicago
Chicago, Illinois, United States
United States, Michigan
Children's Hospital of Michigan
Detroit, Michigan, United States
United States, Nebraska
Archana Chatterjee
Omaha, Nebraska, United States, 68131
United States, Ohio
University Hospital Cased Medical Center Rainbow Babies and Children's Hospital
Cleveland, Ohio, United States
United States, Texas
UT Southwestern Medical Center
Dallas, Texas, United States 收起 <<
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