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异硫氰酸荧光素-葡聚糖 /FITC-Dextran {[allProObj[0].p_purity_real_show]}

货号:A1149843 同义名: 荧光素异硫氰酸酯-葡聚糖

FITC-Dextran 是一种荧光标记的葡聚糖,能够用于细胞内外的示踪和成像研究。FITC-Dextran 主要用于细胞膜通透性、细胞摄取以及血管通透性研究。

FITC-Dextran 化学结构 CAS号:60842-46-8
FITC-Dextran 化学结构
CAS号:60842-46-8
FITC-Dextran 3D分子结构
CAS号:60842-46-8
FITC-Dextran 化学结构 CAS号:60842-46-8
FITC-Dextran 3D分子结构 CAS号:60842-46-8
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FITC-Dextran 生物活性

描述 FITC-Dextran (MW 10000) serves as a fluorescent tracer conjugated with fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm). It functions as a marker to detect heat shock-induced cell damage and investigate both early and late stages of apoptosis. Additionally, FITC-Dextran (MW 10000) is utilized in cell permeability assessments, including studies on blood-brain barrier permeability and determination of the degree of blood-brain barrier disruption[1][2][3]. FITC-Dextran (MW 4000) functions as a fluorescent tracer conjugated with fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm). It serves as a marker for detecting heat shock-induced cell damage and investigating both early and late stages of apoptosis. Additionally, FITC-Dextran (MW 4000) is utilized in cell permeability assessments, including studies on blood-brain barrier permeability and determination of the degree of blood-brain barrier disruption[1][2][3]. FITC-Dextran (MW 3000-5000) serves as a fluorescent tracer conjugated with fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm). It functions as a marker to detect heat shock-induced cell damage and investigate both early and late stages of apoptosis. Additionally, FITC-Dextran (MW 3000-5000) is utilized in cell permeability assessments, including studies on blood-brain barrier permeability and determination of the degree of blood-brain barrier disruption[1][2][3]. FITC-Dextran (MW 40000) functions as a fluorescent tracer conjugated with fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm). It serves as a marker to detect heat shock-induced cell damage and investigate both early and late stages of apoptosis. Additionally, FITC-Dextran (MW 40000) is utilized in cell permeability assessments, including studies on blood-brain barrier permeability and determination of the degree of blood-brain barrier disruption[1][2][3]. FITC-Dextran (MW 150000) serves as a fluorescent tracer conjugated with fluorescein isothiocyanate (FITC) dextran (Ex=491 nm; Em=518 nm). It functions as a marker to detect heat shock-induced cell damage and investigate both early and late stages of apoptosis. Additionally, FITC-Dextran (MW 150000) is employed in perfusion studies in animals or in fluorescence microlymphography to study processes affecting the permeability of the blood-brain barrier (BBB)[6]. FITC-Dextran (MW 150000) serves as a fluorescent tracer for investigating cell permeability[7].
体外研究

FITC-Dextran (MW 20000) serves as a fluorescent tracer conjugated with fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm). It functions as a marker to detect heat shock-induced cell damage and investigate both early and late stages of apoptosis. Additionally, FITC-Dextran (MW 20000) is utilized in cell permeability assessments, including studies on blood-brain barrier permeability and determination of the degree of blood-brain barrier disruption[1][2][3].

FITC-Dextran (MW 70000) serves as a fluorescent tracer conjugated with fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm). It functions as a marker to detect heat shock-induced cell damage and investigate both early and late stages of apoptosis. Additionally, FITC-Dextran (MW 70000) is utilized in cell permeability assessments, including studies on blood-brain barrier permeability and determination of the degree of blood-brain barrier disruption[1][2][3].

FITC-Dextran (MW 110000) serves as a fluorescent tracer conjugated with fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm). It functions as a marker to detect heat shock-induced cell damage and investigate both early and late stages of apoptosis. Additionally, FITC-Dextran (MW 110000) is utilized in cell permeability assessments, including studies on blood-brain barrier permeability and determination of the degree of blood-brain barrier disruption[1][2][3].

FITC-Dextran (MW 500000) serves as a fluorescent tracer conjugated with fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm). It functions as a marker to detect heat shock-induced cell damage and investigate both early and late stages of apoptosis. Additionally, FITC-Dextran (MW 500000) is utilized in cell permeability assessments, including studies on blood-brain barrier permeability and determination of the degree of blood-brain barrier disruption[1][2][3].

FITC-Dextran (MW 2000000) functions as a fluorescent tracer conjugated with fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm). It serves as a marker to detect heat shock-induced cell damage and investigate both early and late stages of apoptosis. Additionally, FITC-Dextran (MW 2000000) is utilized in cell permeability assessments, including studies on blood-brain barrier permeability and determination of the degree of blood-brain barrier disruption[1][2][3].

FITC-Dextran 参考文献

[1]Moumaris M, et al. Fluorescein isothiocyanate-dextran can track apoptosis and necrosis induced by heat shock of peripheral blood mononuclear cells and HeLa cells[J]. Open Biological Sciences Journal, 2015, 1(1).

[2]Natarajan R, et al. Fluorescein Isothiocyanate (FITC)-Dextran Extravasation as a Measure of Blood-Brain Barrier Permeability. Curr Protoc Neurosci. 2017 Apr 10;79:9.58.1-9.58.15.

[3]Eriksson I, et al. Analysis of Lysosomal pH by Flow Cytometry Using FITC-Dextran Loaded Cells. Methods Mol Biol. 2017;1594:179-189.

[4]Bolliner A,et al.,Fluorescence microlymphography: diagnostic potential in lymphedema and basis for the measurement of lymphatic pressure and flow velocity. Lymphology. 2007 Jun;40(2):52-62.

[5]Ishii T, et al., Accumulation of macromolecules in brain parenchyma in acute phase of cerebral infarction/reperfusion. Brain Res. 2010 Mar 19;1321:164-8.

FITC-Dextran 技术信息

CAS号60842-46-8
分子式
分子量
别名 荧光素异硫氰酸酯-葡聚糖
运输蓝冰
存储条件

In solvent -20°C:3-6个月-80°C:12个月

Pure form Keep in dark place,Sealed in dry,2-8°C

溶解方案

H2O: 15 mg/mL,配合低频超声助溶

DMSO: 12 mg/mL,配合低频超声,并水浴加热至45℃助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

配制的工作液建议现用现配,短期内尽快用完。 以下溶剂前显示的百分比是指该溶剂在终溶液中的体积占比;如在配制过程中出现沉淀、析出现象,可以通过加热和/或超声的方式助溶
方案一
动物实验配方
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