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Duloxetine/度洛西汀 {[allProObj[0].p_purity_real_show]}

货号:A683411 同义名: (S)-Duloxetine; LY248686

Duloxetine is a serotonin-norepinephrine reuptake inhibitor with Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD).

Duloxetine/度洛西汀 化学结构 CAS号:116539-59-4
Duloxetine/度洛西汀 化学结构
CAS号:116539-59-4
Duloxetine/度洛西汀 3D分子结构
CAS号:116539-59-4
Duloxetine/度洛西汀 化学结构 CAS号:116539-59-4
Duloxetine/度洛西汀 3D分子结构 CAS号:116539-59-4
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Duloxetine/度洛西汀 纯度/质量文件 产品仅供科研

货号:A683411 标准纯度: {[allProObj[0].p_purity_real_show]}
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Duloxetine/度洛西汀 生物活性

靶点
  • 5-HT

描述 Duloxetine is a serotonin-norepinephrine reuptake inhibitor with Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD).

Duloxetine/度洛西汀 临床研究

NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT00190645 Stress Urinary Incontinence Phase 3 Completed - United States, Colorado ... 展开 >> For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST) or speak with your personal physician Denver, Colorado, United States, 80220 Canada, Ontario For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559,1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST) or speak with your personal physician Oakville, Ontario, Canada, L6H3P1 收起 <<
NCT00387413 Hyperalgesia Phase 1 Completed - United Kingdom ... 展开 >> GSK Investigational Site Cambridge, Cambridgeshire, United Kingdom, CB2 0QQ 收起 <<
NCT00945945 Osteoarthritis Knee Pain Phase 3 Completed - -

Duloxetine/度洛西汀 参考文献

[1]De Berardis D, Conti CM, et al. The effect of newer serotonin-noradrenalin antidepressants on cytokine production: a review of the current literature. Int J Immunopathol Pharmacol. 2010 Apr-Jun;23(2):417-22.

[2]Wang SY, Calderon J, et al. Block of neuronal Na+ channels by antidepressant duloxetine in a state-dependent manner. Anesthesiology. 2010 Sep;113(3):655-65.

Duloxetine/度洛西汀 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.36mL

0.67mL

0.34mL

16.81mL

3.36mL

1.68mL

33.62mL

6.72mL

3.36mL

Duloxetine/度洛西汀 技术信息

CAS号116539-59-4
分子式C18H19NOS
分子量 297.41
SMILES Code CNCC[C@H](OC1=CC=CC2=C1C=CC=C2)C3=CC=CS3
MDL No. MFCD06801358
别名 (S)-Duloxetine; LY248686
运输蓝冰
存储条件

In solvent -20°C:3-6个月-80°C:12个月

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