同义名 : | (S)-Duloxetine;LY248686 | |
CAS号 : | 116539-59-4 | |
货号 : | A683411 | |
分子式 : | C18H19NOS | |
纯度 : | 98+% | |
分子量 : | 297.415 | |
MDL号 : | MFCD06801358 | |
存储条件: |
粉末 Sealed in dry,2-8°C 液体 -20°C:3-6个月-80°C:12个月 |
|
溶解度 : | - | |
动物实验配方: |
生物活性 | |||
---|---|---|---|
靶点 |
|
||
描述 | Duloxetine is a serotonin-norepinephrine reuptake inhibitor with Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD). |
临床研究 | |||||
---|---|---|---|---|---|
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
NCT00190645 | Stress Urinary Incontinence | Phase 3 | Completed | - | United States, Colorado ... 展开 >> For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST) or speak with your personal physician Denver, Colorado, United States, 80220 Canada, Ontario For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559,1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST) or speak with your personal physician Oakville, Ontario, Canada, L6H3P1 收起 << |
NCT00387413 | Hyperalgesia | Phase 1 | Completed | - | United Kingdom ... 展开 >> GSK Investigational Site Cambridge, Cambridgeshire, United Kingdom, CB2 0QQ 收起 << |
NCT00945945 | Osteoarthritis Knee Pain | Phase 3 | Completed | - | - |
实验方案 | |||
---|---|---|---|
1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
3.36mL 0.67mL 0.34mL |
16.81mL 3.36mL 1.68mL |
33.62mL 6.72mL 3.36mL |
参考文献 |
---|