2, 5-Dioxopyrrolidin-1-yl 2-(cyclooct-2-ynyloxy)acetate is a PEGn linker for antibody-drug-conjugation (ADC).
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描述 | Cyclooctyne-O-NHS ester is a cleavable linker employed in the creation of antibody-drug conjugates (ADCs)[1]. Cyclooctyne-O-NHS ester functions as a click chemistry reagent, featuring an Alkyne group that enables it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide group-containing molecules. |
计算器 | ||||
存储液制备 | 1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
3.58mL 0.72mL 0.36mL |
17.90mL 3.58mL 1.79mL |
35.81mL 7.16mL 3.58mL |
CAS号 | 1425803-45-7 |
分子式 | C14H17NO5 |
分子量 | 279.288 |
别名 | |
运输 | 蓝冰 |
存储条件 |
液体 -20°C:3-6个月-80°C:12个月 粉末 Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
溶解度 |
DMSO: 105 mg/mL(375.96 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO |
动物实验配方 |