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氯己定 /Chlorhexidine {[allProObj[0].p_purity_real_show]}

货号：A814733

Chlorhexidine is an antibacterial used as an antiseptic and for other applications.

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Type	HazMat fee for 500 gram (Estimated)
Excepted Quantity	USD 0.00
Limited Quantity	USD 15-60
Inaccessible (Haz class 6.1), Domestic	USD 80+
Inaccessible (Haz class 6.1), International	USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic	USD 100+
Accessible (Haz class 3, 4, 5 or 8), International	USD 200+

Chlorhexidine 化学结构
CAS号：55-56-1

Chlorhexidine 3D分子结构
CAS号：55-56-1

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Chlorhexidine 纯度/质量文件产品仅供科研

货号：A814733 标准纯度： {[allProObj[0].p_purity_real_show]} 产品说明书

批次查询：批次纯度: COA SDS NMR HPLC CNMR LC-MS

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Chlorhexidine 生物活性

描述

Chlorohexidine is cationic bis-biguanide broad spectrum antiseptic with both anti-plaque and antibacterial properties^[3]. Topical application of chlorohexidine resulted in a marked reduction of plaque formation, substantial improvement in gingival condition, and considerable decrease in the germ content of the plaque. A significant reduction in oral germ count could be determined in the experimental animals. However, it was not possible to observe a significant inhibition of caries production^[4]. Combined use of fluorides and chlorohexidine was seen to exert an inhibitory action on the progress of dental caries^[5]. Chlorehexidine (0.2%) and a phenolic mouth rinse significantly reduced plaque growth and gingival inflammation compared to a placebo mouthrinse, however chlorhexidine rinse was more effective against plaque regrowth than the phenolic rinse^[6].

Chlorhexidine 临床研究

NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点
NCT03401801	Neuropathic Pain	Not Applicable	Recruiting	February 17, 2019	Korea, Republic of ... 展开 >> Seoul National University Hospital Recruiting Seoul, Korea, Republic of Contact: Jee Youn Moon, M.D. 82-10-5299-2036 jymoon0901@gmail.com Principal Investigator: Jee Youn Moon, M.D. 收起 <<
NCT02662374	Oral Mucositis	Phase 4	Unknown	May 2016	-
NCT03161717	Epidural Analgesia	Not Applicable	Recruiting	March 2019	Korea, Republic of ... 展开 >> Korea University Guro Hospital Recruiting Seoul, Korea, Republic of, 08308 Contact: Seung-hoe Song, MBE 82-2-2626-1635 ssessong@korea.ac.kr Contact: Da-in Lee 82-2-2626-2279 0124dain@gmail.com Principal Investigator: Sang Sik Choi, MD, PhD Sub-Investigator: Chung Hun Lee, MD Sub-Investigator: Mi Kyoung Lee, MD, PhD 收起 <<

Chlorhexidine 参考文献

[1]Sheikh Hasani Y, Paryab M, et al. The Effect of Disinfection with Chlorhexidine on the Shear Bond Strength of Equia Resin-Modified Glass Ionomer Cement to Dentin in Permanent Teeth after Two Thermocycling Protocols. J Dent (Shiraz). 2017 Dec;18(4):265-271.

[2]Strain GM. Chlorhexidine. J Small Anim Pract. 2017 Nov 28.

[3]Prasad KA, John S, Deepika V, Dwijendra KS, Reddy BR, Chincholi S. Anti-Plaque Efficacy of Herbal and 0.2% Chlorhexidine Gluconate Mouthwash: A Comparative Study. J Int Oral Health. 2015;7(8):98‐102

[4]Treide A, Klimm W, Morosova L. Klinische und tierexperimentelle Untersuchungen üben den Einfluss lokalapplizierten Chlorhexidins auf Plaquebildung, Keimflora und Kariesbefall [Clinical and experimental animal studies made to determine the influence of topically applied chlorohexidine upon plaque formation, germ flora, and caries production (author's transl)]. Zahn Mund Kieferheilkd Zentralbl. 1980;68(2):106‐115

[5]Novikov LL, Treide A, Kolesnik AG, Stösser L, Schaper R. Der Einfluss anorganischer und organischer Fluoride in Kombination mit Molybdän und Chlorhexidin auf Stoffwechselprozesse, Fluoridgehalt und Kariesbefall der Zähne von Wistarratten [Effects of inorganic and organic fluorides combined with molybdenum and chlorohexidine upon processes of metabolism, fluoride content, and cariosity of the teeth of Wistar rats (author's transl)]. Zahn Mund Kieferheilkd Zentralbl. 1980;68(1):3‐8

[6]Goutham BS, Manchanda K, Sarkar AD, Prakash R, Jha K, Mohammed S. Efficacy of two commercially available Oral Rinses - Chlorohexidine and Listrine on Plaque and Gingivitis - A Comparative Study. J Int Oral Health. 2013;5(4):56‐61

Chlorhexidine 实验方案

计算器

存储液制备

1mg

5mg

10mg

1 mM

5 mM

10 mM

1.98mL

0.40mL

0.20mL

9.89mL

1.98mL

0.99mL

19.78mL

3.96mL

1.98mL

Chlorhexidine 技术信息

CAS号	55-56-1
分子式	C₂₂H₃₀Cl₂N₁₀
分子量	505.447

别名
运输	蓝冰

存储条件

液体 -20°C:3-6个月-80°C:12个月

粉末 Keep in dark place,Inert atmosphere,2-8°C

溶解度

DMSO: 25 mg/mL(49.46 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

动物实验配方

临床研究

NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点

NCT03401801	Neuropathic Pain	Not Applicable	Recruiting	February 17, 2019	Korea, Republic of ... 展开 >> Seoul National University Hospital Recruiting Seoul, Korea, Republic of Contact: Jee Youn Moon, M.D. 82-10-5299-2036 jymoon0901@gmail.com Principal Investigator: Jee Youn Moon, M.D. 收起 <<
NCT02662374	Oral Mucositis	Phase 4	Unknown	May 2016	-
NCT03161717	Epidural Analgesia	Not Applicable	Recruiting	March 2019	Korea, Republic of ... 展开 >> Korea University Guro Hospital Recruiting Seoul, Korea, Republic of, 08308 Contact: Seung-hoe Song, MBE 82-2-2626-1635 ssessong@korea.ac.kr Contact: Da-in Lee 82-2-2626-2279 0124dain@gmail.com Principal Investigator: Sang Sik Choi, MD, PhD Sub-Investigator: Chung Hun Lee, MD Sub-Investigator: Mi Kyoung Lee, MD, PhD 收起 <<
NCT03093194	A Known Allergy to Antiseptic ... 展开 >>Soap Women Who Had Any Infection in the Perioperative Period A Known Allergy to Chlorohexidine Alcohol or Shellfis 收起 <<	Not Applicable	Not yet recruiting	April 30, 2020	-
NCT03640507	Cesarean Section; Infection ... 展开 >> Surgical Site Infection 收起 <<	Phase 2 Phase 3	Recruiting	June 2019	United States, New York ... 展开 >> New York Presbyterian Hospital at Columbia University and Children's Hospital of New York Recruiting New York, New York, United States, 10032 Contact: Cassandra R. Duffy, MD 929-286-0292 crd2130@columbia.edu 收起 <<
NCT02628938	Oral Malodor ... 展开 >>Halitosis 收起 <<	Phase 2	Completed	-	Saudi Arabia ... 展开 >> Riyadh colleges of dentistry and pharmacy Riyadh, Saudi Arabia, 11681 收起 <<
NCT02385708	Surgical Site Infection	Not Applicable	Completed	-	United States, Tennessee ... 展开 >> Vanderbilt University Nashville, Tennessee, United States, 37212 收起 <<
NCT02628938	-		Completed	-	-
NCT03590977	Caries, Dental	Not Applicable	Not yet recruiting	October 1, 2019	-
NCT03195582	Implant Infection ... 展开 >> Bone Loss 收起 <<	Phase 1 Phase 2	Not yet recruiting	December 2018	-
NCT03115892	Halitosis	Phase 1 Phase 2	Enrolling by invitation	December 1, 2017	Egypt ... 展开 >> Oral An Dental Medicine Faculty Cairo, Egypt 收起 <<

氯己定 /Chlorhexidine {[allProObj[0].p_purity_real_show]}

Chlorhexidine 纯度/质量文件产品仅供科研

全球学术期刊中引用的产品

Chlorhexidine 质控信息

Chlorhexidine 生物活性

Chlorhexidine 临床研究

Chlorhexidine 参考文献

Chlorhexidine 实验方案

Chlorhexidine 技术信息

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氯己定 /Chlorhexidine {[allProObj[0].p_purity_real_show]}

Chlorhexidine 纯度/质量文件 产品仅供科研

全球学术期刊中引用的产品

Chlorhexidine 质控信息

Chlorhexidine 生物活性

Chlorhexidine 临床研究

Chlorhexidine 参考文献

Chlorhexidine 实验方案

Chlorhexidine 技术信息

最近浏览的产品

大规格询价

摩尔计算器

靶点

总药量计算器

工作液计算器

细胞研究

临床研究

确认信息

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Chlorhexidine 纯度/质量文件产品仅供科研