There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.
Type
HazMat fee for 500 gram (Estimated)
Excepted Quantity
USD 0.00
Limited Quantity
USD 15-60
Inaccessible (Haz class 6.1), Domestic
USD 80+
Inaccessible (Haz class 6.1), International
USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic
USD 100+
Accessible (Haz class 3, 4, 5 or 8), International
Catalase from Aspergillus niger plays a crucial role in metabolizing H2O2 and reactive oxygen species (ROS), with significant changes observed in its expression and localization in tumors[1].
体外研究
Catalase is an enzyme that not only metabolizes H2O2 but also interacts with various other substrates. Its active site includes an iron atom. Human catalase consists of four identical subunits, with each subunit comprising four distinct domains and a single prosthetic heme group. The four domains are: (1) a N-terminal arm featuring a distal histidine, a crucial amino acid for the catalase reaction; (2) a β-barrel domain with eight β-barrels in an antiparallel arrangement and six α-helical insertions, which create the protein’s hydrophobic core essential for its three-dimensional structure; (3) a connection domain that includes the tyrosine residue binding to the heme group; and (4) an α-helical domain important for NADPH binding[1].
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